Effect of Nasal Spray Dexmedetomidine on Emergence Delirium Prevention in Total Hip Replacement

This study is testing whether a nasal spray version of dexmedetomidine — a calming medication — given before surgery can prevent emergence delirium (a state of confusion and agitation that some patients experience right after waking from general anesthesia) in older adults having hip replacement surgery. **You may be eligible if...** - You are 60 years or older - You are scheduled for total hip replacement under general anesthesia - You are classified as ASA grade II or III (mild to moderate medical conditions) **You may NOT be eligible if...** - You have an allergy or contraindication to dexmedetomidine - You have severe nasal problems or a significantly deviated nasal anatomy - You have a very slow heart rate, serious heart block, severe heart failure, or a pacemaker - You have had a recent heart attack, stroke, or severe brain condition Talk to your doctor to see if this trial is right for you.