RecruitingNot ApplicableNCT06582121

Study of Sleep Disorders in Prodromal and Definite Parkinsons Disease

Controlled, Multicenter Study of Sleep Disorders in Prodromal and Definite Parkinsons Disease

Sponsor

Assistance Publique - Hôpitaux de Paris

Enrollment

457 participants

Start Date

Mar 18, 2025

Study Type

INTERVENTIONAL

Conditions

Multicenter controlled study of sleep disorders in isolated REM Behavior Disorder and Parkinson\'s disease (SOMPARK)

Min Age: 18 Years

Common to all groups:
Age superior 18 years
Patients who have received complete information about the study from an investigator and who fully consent to participate.
For Parkinson Disease (PD):
Patients followed for PD diagnosed according to international criteria for the diagnosis of PD (MDS criteria),
A MoCA score greater than 20/30
No treatment with deep brain stimulation.
For REM Sleep Behavior Disorder (RBD):
Diagnosis of RBD according to ICSD-3 criteria: presence on polysomnography of an abnormal elevation of muscle tone during REM sleep (more than 18% of REM sleep without chin atonia) and/or the presence of REM sleep behaviors on video-polysomnography,
Absence of progressive neurodegenerative pathology: absence of diagnostic criteria for PD, multiple system atrophy, or Lewy body dementia.
For healthy controls:
\- No neurological or psychiatric disease