Nicotinic Acid for the Treatment of Alzheimer's Disease

This study tests whether nicotinic acid (a form of vitamin B3) can slow the progression of Alzheimer's disease or improve thinking and memory in people with mild to moderate dementia. Nicotinic acid is inexpensive and widely available, and early research suggests it may support brain cell energy and reduce inflammation. **You may be eligible if...** - You are between 60 and 85 years old (male or female) - You have been diagnosed with Alzheimer's disease in the mild to moderate range - Your score on the Mini Mental Status Exam (MMSE) is between 14 and 24 - You are on a stable dose of Alzheimer's medication (or none) for at least 30 days - You have a caregiver or family member who sees you in person at least 3 days per week **You may NOT be eligible if...** - You have liver disease or a history of liver problems - You have had a recent heart attack or stroke - You are allergic to niacin or related compounds Talk to your doctor to see if this trial is right for you.