RecruitingNot ApplicableNCT06584123

Molecular Pituitary Imaging Using 18F-FET PET

Exploring the Potential for 18F-fluoro-ethyl-tyrosine (18F-FET) to Enable Wider Access to Molecular Imaging for Patients With Pituitary Adenomas (FET-pit-PET Study)


Sponsor

University of Cambridge

Enrollment

20 participants

Start Date

Sep 3, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this single centre pilot study is to explore whether 18F-fluoro-ethyl-tyrosine PET (FET-PET) yields comparable findings to 11C-methionine PET (Met-PET) for the localisation of pituitary tumours.


Eligibility

Min Age: 18 YearsMax Age: 100 Years

Inclusion Criteria4

  • Participant is willing and able to give informed consent for participation in the study
  • Male or female, age 18 or above
  • Presence of pituitary adenoma suspected on the basis of clinical/biochemical and/or radiological findings
  • Previous 11C-Met-PET/CT

Exclusion Criteria5

  • Inability to give informed consent
  • Pregnancy or suspected pregnancy
  • Inability to lie supine for 30-60 minutes
  • Patient body habitus above scanner dimensions
  • Known allergy to intravenous radiographic contrast agents

Interventions

DIAGNOSTIC_TEST18F-Fluoro-ethyl-tyrosine (FET) PET

18F-Fluoro-ethyl-tyrosine PET study of the pituitary


Locations(1)

Cambridge University Hospitals

Cambridge, Cambridgeshire, United Kingdom

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NCT06584123


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