RecruitingNCT06584266

Multimodal Cardiac Imaging Registry in Patients with Atrial Fibrillation

Multimodal, Multicentre Registry of Clinical and Imaging Data to Develop Predictive Models Based on Artificial Intelligence to Support the Diagnostic and Therapeutic Process for Patients with Atrial Fibrillation Undergoing Catheter Ablation and Cardioversion.


Sponsor

University in Zielona Góra

Enrollment

3,000 participants

Start Date

Jan 1, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational registry is to collect a curated dataset of multimodal imaging data that will serve for development of artificial-intelligence based solutions for prediction of risk and outcomes in patients with atrial fribrillation. Type of study: observational study Study Participants: Patients with atrial fibrillation or atrial flutter who undergo clinically indicated transesophageal echocardiography before catheter ablation or cardioversion. We hypothesize, that automatic analysis of video images of transthoracic echocardiography with deep learning combined with clinical data can predict the presence of left atrial appendage thrombus (LAT). Therefore, our main aim is to create and validate an artificial intelligence model to predict the presence of LAT based on automatic analysis of transthoracic echocardiography with artificial intelligence.


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • \- All patients with AF or AFl in whom TEE will be performed (to assess their eligibility for cardioversion or ablation), hospitalized in a participating center during study period (all consecutive patients).

Exclusion Criteria1

  • Age\<18, lack of informed, written consent to the TEE

Interventions

DIAGNOSTIC_TESTTransoesophageal echocardiography

Imaging data obtained with transoesophageals echocardiography will be retained as well as data from transthoracic echocardiography and from other imaging modalities, if available

PROCEDURECatheter ablation

Cathether ablation of atrial fibrillation substrate using one of available methods.


Locations(7)

St. Anne Hospital

Brno, Czechia

Nowa Sol Multidyscyplinary Hospital

Nowa Sól, Lubusz Voivodeship, Poland

Medical University of Silesia

Katowice, Poland

John Paul II Hospital

Krakow, Poland

Military Institute of Medicine National Research Institute

Warsaw, Poland

National Institute of Cardiology

Warsaw, Poland

Collegium Medicum, University of Zielona Góra

Zielona Góra, Poland

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NCT06584266


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