RecruitingPhase 1NCT06585462

Single and Multiple Ascending Dose Study of AMG 513 in Participants With Obesity

A Phase 1, Randomized, Double-blind, Placebo-controlled, Single Ascending Dose and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AMG 513 in Participants With Obesity

Sponsor

Amgen

Enrollment

80 participants

Start Date

Sep 9, 2024

Study Type

INTERVENTIONAL

Conditions

Cardiometabolic disease

Summary

The primary objective of this study is to assess the safety and tolerability of AMG 513 after single and multiple doses.

Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called AMG 513, a drug called AMG 513, and others for people with cardiometabolic disease. The study is currently recruiting participants at 7 locations. People eligible for this study include aged 18 Years to 65 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGAMG 513

AMG 513 will be administered by SC or IV injection.

DRUGPlacebo

Placebo will be administered by SC or IV injection.

DRUGAMG 513

AMG 513 will be administered by SC injection.

DRUGPlacebo

Placebo will be administered by SC injection.

Locations(10)

Anaheim Clinical Trials

Anaheim, California, United States

Orange County Research Center

Lake Forest, California, United States

Fomat Medical Research

Oxnard, California, United States

Translational Clinical Research LLC

Aventura, Florida, United States

Clinical Neuroscience Solutions - Jacksonville

Jacksonville, Florida, United States

New Horizon Research Center

Miami, Florida, United States

Clinical Pharmacology of Miami, LLC

Miami, Florida, United States

Rophe Adult and Pediatric Medicine/Sky Clinical Research Network Group

Union City, Georgia, United States

Lillestol Research LLC

Fargo, North Dakota, United States

Pinnacle Clinical Research

Austin, Texas, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

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NCT06585462

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