Adjuvant Concurrent Immunotherapy and Radiotherapy for the Treatment of Bladder Cancer

This study is testing whether adding immunotherapy (a cancer-fighting drug that activates your immune system) to radiation therapy after bladder removal surgery can reduce the risk of bladder cancer coming back in people with high-risk disease. **You may be eligible if...** - You have urothelial carcinoma of the bladder (including certain variant subtypes) - You are considered high risk for recurrence after surgery - You have not previously received immunotherapy (anti-PD1/PD-L1 therapy) - Your overall health and organ function are within acceptable ranges **You may NOT be eligible if...** - You have already received immunotherapy for bladder cancer - You have active autoimmune disease requiring systemic treatment - You have severe immune deficiency or are on high-dose steroids - You have active infections, including HIV or active hepatitis - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.