RecruitingNot ApplicableNCT06588764

Modified Orbital Decompression in the Treatment of Moderate-to-severe Grave's Ophthalmopathy

Modified Deep Lateral Wall Decompression and/or Deep Medial Wall Decompression for Moderate-to-severe Grave's Ophthalmopathy: a Prospective Study


Sponsor

Sun Yat-sen University

Enrollment

50 participants

Start Date

Sep 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

To investigate the efficacy and safety of modified deep lateral wall decompression and/or medial wall decompression for Moderate-to-severe Grave's Ophthalmopathy.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria4

  • EUGOGO/NOSPECS grade was moderate-to-severe thyroid associate ophthalmopathy;
  • CAS≤3 score;
  • stable thyroid function for at least 6 months;
  • able and willing to participate in clinical trials and ensure regular follow-up;

Exclusion Criteria4

  • any uncontrollable clinical problems (severe mental, neurological, cardiovascular, respiratory and other systemic diseases and malignant tumors);
  • B-ultrasound or CT, MRI found other diseases causing exophthalmos (intraorbital space occupying lesion, inflammatory pseudotumor, neurofibroma, etc.);
  • uveitis, glaucoma, high myopia, diabetic retinopathy and other eye diseases
  • those who were considered by the researchers to be excluded

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Interventions

PROCEDUREmodified deep lateral and/or medial wall decompression

Modified deep lateral orbital wall decompression is based on traditional outer wall decompression with combined abrasion of the deep outer orbital wall (including the greater pterygoid wing) to achieve adequate enlargement of the orbital cavity.


Locations(1)

Zhongshan Ophthalmic Center, Sun Yat-sen University

Guangzhou, Guangdong, China

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NCT06588764


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