RecruitingPhase 1NCT06589245

Inhaled Ciclesonide Study in Preterm Infants

The Safety and Toxicity of Inhaled Ciclesonide (i.e., Alvesco) in Preterm Infants at Risk for Developing Bronchopulmonary Dysplasia


Sponsor

Venkatesh Sampath

Enrollment

30 participants

Start Date

Sep 16, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Our overall objective is to conduct a safety study with inhaled ciclesonide to evaluate known glucocorticoids (sGC)-related acute and intermediate toxic effects while measuring for the first time in neonates its systemic absorption and potential bioactivity (i.e. activation of primary target, the GR, in blood cells).


Eligibility

Min Age: 8 DaysMax Age: 35 Days

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Alvesco Inhalant Product for people with bronchopulmonary dysplasia. The study is currently recruiting participants at 1 location. People eligible for this study include aged 8 Days to 35 Days.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGAlvesco Inhalant Product

Inhaled Alvesco will be administered daily for 14 days at escalating doses of 80mcg and 160mcg.


Locations(1)

Children's Mercy Kansas City

Kansas City, Missouri, United States

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NCT06589245


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