High Definition Medicine for Solid Tumors Oncology

This study is using wearable devices and digital health monitoring to collect detailed, real-world data about how people with solid tumors (primarily breast, lung, or colon cancer) respond to first-line treatment. The goal is to better understand individual patterns that predict treatment success or complications. **You may be eligible if...** - You have a confirmed advanced (stage III or IV) solid tumor cancer that is not being treated with the goal of cure - You are about to start your first-line cancer treatment - Your ECOG performance status is less than 2 (you are up and about for more than half the day) - You are able to use a wearable device and have a smartphone with internet access - Preference is given to women with hormone-positive, HER2-negative breast cancer; women with any subtype of lung cancer; or patients with any subtype of colon cancer **You may NOT be eligible if...** - Your treatment plan is blinded (you don't know which treatment you are receiving in a trial) - You cannot use or carry a wearable device Talk to your doctor to see if this trial is right for you.