Cryodevitalization for the Treatment of Early Stage Lung Cancer, CRYSTAL Trial

This study (CRYSTAL Trial) is testing a technique called cryodevitalization — using extreme cold to destroy cancer cells — on small, early-stage lung tumors during a bronchoscopy procedure, before standard surgical removal. The goal is to see if this improves outcomes. **You may be eligible if...** - You have a single lung nodule (spot) that is 3 cm or smaller and confirmed to be cancerous or a single metastatic spot - The nodule is located in the outer part of the lung, away from major blood vessels and airways - Your doctors have determined that surgery is a safe and appropriate option for you - You are over 18 years old **You may NOT be eligible if...** - Your tumor is located near the central airway, major blood vessels, heart, or spine - Your expected survival is less than 6 months - You have lesions inside the airways suspected of being cancer - You have a blood clotting disorder that cannot be corrected - You have nodules in multiple locations in the lung Talk to your doctor to see if this trial is right for you.