Kidney Function in People With Cystic Fibrosis in the Era of HEMT

This study is looking at how kidney function changes over time in people with cystic fibrosis (CF), particularly now that highly effective new medications (called HEMT, like Trikafta) are widely used. It also includes healthy volunteers for comparison. **You may be eligible if...** - You have been diagnosed with cystic fibrosis - For the outpatient group: you are older than 30 and can give consent - For the inpatient group: you are older than 7, have been hospitalized for a lung infection (pulmonary exacerbation), and can provide a urine sample - For healthy controls: you are between 30 and 50 years old with no known health problems **You may NOT be eligible if...** - You have had an organ transplant or have an immune deficiency - You have a current or previous cancer diagnosis - You are pregnant or breastfeeding - You are currently on dialysis Talk to your doctor to see if this trial is right for you.