Acute Kidney Injury Clinical Trials

130 recruiting

Acute Kidney Injury Trials at a Glance

151 actively recruiting trials for acute kidney injury are listed on ClinicalTrialsFinder across 6 cities in 40 countries. The largest study group is Not Applicable with 49 trials, with the heaviest enrollment activity in Birmingham, San Francisco, and Baltimore. Lead sponsors running acute kidney injury studies include Seoul National University Hospital, Assistance Publique - Hôpitaux de Paris, and Universität Münster.

Browse acute kidney injury trials by phase

Treatments under study

About Acute Kidney Injury Clinical Trials

Looking for clinical trials for Acute Kidney Injury? There are currently 130 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Acute Kidney Injury trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Acute Kidney Injury clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 151 trials

Recruiting

Acute Normovolemic Hemodilution on Urine Neutrophil Gelatinase-associated Lipocalin Levels

Acute Kidney Injury
University of Maryland, Baltimore100 enrolled1 locationNCT05349292
Recruiting
Not Applicable

LoW Dose-Intensity vs. Standard Dose-Intensity COntinuous Renal ReplaceMent Therapy in Critically Ill Patients (WISDOM)

Acute Kidney InjuryDialysis; Complications
University of Alberta100 enrolled9 locationsNCT06446739
Recruiting
Phase 3

Bleeding Reduction in Acute and Chronic Kidney Patients Having Surgery (BRACKETS) Pilot Trial

SurgeryChronic Kidney DiseasesAcute Kidney Injury+1 more
Hamilton Health Sciences Corporation100 enrolled3 locationsNCT06337838
Recruiting
Not Applicable

Neutrophil and Monocyte Deactivation Via the SeLective CytopheretIc Device - A Randomized Clinical Trial in Acute Kidney Injury

Acute Kidney Injury
SeaStar Medical339 enrolled38 locationsNCT05758077
Recruiting
Not Applicable

A Methodological Study to Learn More About Kidney Function in Healthy People and in People With Reduced Kidney Function

Acute Kidney Injury, Renal Insufficiency
Bayer50 enrolled1 locationNCT07368712
Recruiting

Effectiveness-Implementation Evaluation of Acute Kidney Injury Decision Support

Acute Kidney Injury
Johns Hopkins University200,000 enrolled1 locationNCT06840210
Recruiting
Not Applicable

Peri-procedural Hydration to Prevent Acute Kidney Injury After Pulsed Field Ablation for Atrial Fibrillation

Acute Kidney InjuryAtrial Fibrillation (AF)
Beijing Anzhen Hospital290 enrolled1 locationNCT07490808
Recruiting
Phase 3

Safety Evaluation of Prismocitrate 18 in Patients Receiving CRRT

Acute Kidney Injury (AKI)Regional Citrate Anticoagulation (RCA)Continuous Renal Replacement Therapy (CRRT)
Vantive Health LLC40 enrolled14 locationsNCT05399537
Recruiting
Phase 1Phase 2

Theophylline Prophylaxis During Hypothermia to Limit Neonatal Nephron Damage

Acute Kidney InjuryHIE
Medical College of Wisconsin30 enrolled1 locationNCT05853601
Recruiting

Prospective Validation of AKI Prediction

Acute Kidney Injury
Adam C Dziorny800 enrolled1 locationNCT06804200
Recruiting
Not Applicable

Validation of a Regional Citrate Anticoagulation Protocol in Critically Ill Patients on Continuous Renal Replacement Therapy

Acute Kidney InjuryICU PatientsContinuous Renal Replacement Therapy (CRRT)+1 more
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau43 enrolled1 locationNCT07514650
Recruiting
Not Applicable

UPTAKE: Using Personalized Risk and Digital Tools to Guide Transitions Following Acute Kidney Events

Acute Kidney Injury
University of Alberta6,046 enrolled2 locationsNCT05806645
Recruiting

The Relationship Between Preoperative Frailty and Postoperative AKI and the Mediating Effect of Intraoperative BP

FrailtyPostoperative Acute Kidney Injury
Lanyue Zhu1,000 enrolled1 locationNCT07030179
Recruiting

Postoperative Acute Kidney Injury in Children Undergoing Major Non-cardiac Surgery

Acute Kidney Injury
Uppsala University2,000 enrolled13 locationsNCT07351149
Recruiting
Phase 4

A Protocol Based-Furosemide Stress Test to Evaluate Renal Recovery During Continuous Renal Replacement Therapy

Acute Kidney Injury
Chiang Mai University80 enrolled1 locationNCT06229990
Recruiting

QUELIMMUNE (SCD-PED) PediAtric SurVeillance REgistry

Acute Kidney InjuryAcute Kidney Injury Due to Sepsis
SeaStar Medical300 enrolled15 locationsNCT06517810
Recruiting

Molecular Prediction of Development, Progression or Complications of Kidney, Immune or Transplantation-related Diseases

CancerMetabolic DiseaseChronic Kidney Diseases+3 more
University Hospital, Toulouse5,000 enrolled1 locationNCT05318196
Recruiting

Histopathological Analysis of Renal Biopsies With Dynamic Full-field Optical Coherence Tomography, a Comparison to Conventional Histopathological Findings for the Diagnosis of Either Acute Kidney Injury or Chronic Kidney Disease in Routine Practices (NEPHROCT)

Chronic Kidney DiseasesAcute Kidney Injury
Centre Hospitalier William Morey - Chalon sur Saône50 enrolled1 locationNCT05728216
Recruiting
Phase 2

Sodium-Glucose Cotransporter-2 Inhibitor for Patients With Acute Cardiorenal Syndrome

Heart FailureAcute Kidney Injury
Yale University130 enrolled2 locationsNCT07273838
Recruiting
Not Applicable

Effects of Creatine Supplementation on Cognitive Measures and Markers of Acute Kidney Injury After Exercise in the Heat

Acute Kidney InjuryExertional Heat Illness
University of Northern Iowa20 enrolled1 locationNCT07472426