Acute Kidney Injury Clinical Trials

176 recruitingLast updated: June 17, 2026

There are 176 actively recruiting acute kidney injury clinical trials across 46 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 4, Phase 1. Top locations include San Francisco, California, United States, Ann Arbor, Michigan, United States, Dallas, Texas, United States. Updated daily from ClinicalTrials.gov.


Acute Kidney Injury Trials at a Glance

176 actively recruiting trials for acute kidney injury are listed on ClinicalTrialsFinder across 6 cities in 46 countries. The largest study group is Not Applicable with 58 trials, with the heaviest enrollment activity in San Francisco, Ann Arbor, and Dallas. Lead sponsors running acute kidney injury studies include Assistance Publique - Hôpitaux de Paris, Centre Hospitalier Universitaire, Amiens, and Hospices Civils de Lyon.

Browse acute kidney injury trials by phase

Treatments under study

About Acute Kidney Injury Clinical Trials

Looking for clinical trials for Acute Kidney Injury? There are currently 146 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Acute Kidney Injury trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Acute Kidney Injury clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 176 trials

Recruiting

Does Urinary TIMP2 and IGFBP7 Can Identify High Risk Patients of Progression From Mild and Moderate to Severe Acute Kidney Injury During Septic Shock?

Acute Kidney InjurySeptic Shock
Centre Hospitalier Universitaire, Amiens110 enrolled1 locationNCT03547414
Recruiting
Not Applicable

A Methodological Study to Learn More About Kidney Function in Healthy People and in People With Reduced Kidney Function

Acute Kidney Injury, Renal Insufficiency
Bayer50 enrolled1 locationNCT07368712
Recruiting
Phase 2

LSALT Peptide for Prevention or Attenuation of Acute Kidney Injury (AKI) in Patients Undergoing On-Pump Cardiac Surgery

Acute Kidney InjuryCardiac Surgery
Arch Biopartners Inc.240 enrolled9 locationsNCT05879432
Recruiting
Not Applicable

UPTAKE: Using Personalized Risk and Digital Tools to Guide Transitions Following Acute Kidney Events

Acute Kidney Injury
University of Alberta6,046 enrolled2 locationsNCT05806645
Recruiting
Phase 1Phase 2

Labile Iron Removal by Adding the Iron Chelator MEX-CD1 to Dialysate in Sepsis-Associated Acute Kidney Injury

SepsisAcute Kidney Injury
Centre Hospitalier Universitaire de Nīmes14 enrolled2 locationsNCT07236463
Recruiting

Assessment of Renal Perfusion Using Ultrasound and Near-Infrared Spectroscopy in Patients Undergoing Minimally Invasive Abdominal Surgery

Acute Kidney InjuryMinimally Invasive Surgical ProceduresRenal Perfusion
Istanbul University - Cerrahpasa51 enrolled1 locationNCT07635160
Recruiting
Not Applicable

Initial Drainage Method and Flexible Ureteroscopy Outcomes in Calculous Anuria

Acute Kidney InjuryObstructive UropathyCalculous Anuria+1 more
Beni-Suef University90 enrolled3 locationsNCT07627880
Recruiting
Phase 2

Intravesical Aminophylline for Urgent Ureteral Stenting in Acute Calculous Anuria

Acute Kidney InjuryUreteral CalculiAcute Calculous Anuria+1 more
Beni-Suef University72 enrolled1 locationNCT07617948
Recruiting
Not Applicable

A Study to Understand How Cardiac Surgery-associated Acute Kidney Injury Develops in Participants Who Undergo Heart Surgery With the Use of Heart-lung Machine

Cardiac Surgery associated Acute kidney injury
Bayer200 enrolled4 locationsNCT06772025
Recruiting
Phase 2

Study of the Relaxin Agonist R2R01 in Patients at High Risk for Cardiac Surgery Associated- Acute Kidney Injury

Acute Kidney Injury
River 2 Renal Corp.430 enrolled1 locationNCT07625553
Recruiting
Not Applicable

CTSN Embolic Protection Trial

Acute Kidney InjuryCoronary Artery DiseaseDelirium+2 more
Icahn School of Medicine at Mount Sinai842 enrolled28 locationsNCT06027788
Recruiting
Phase 3

Bleeding Reduction in Acute and Chronic Kidney Patients Having Surgery (BRACKETS) Pilot Trial

SurgeryChronic Kidney DiseasesAcute Kidney Injury+1 more
Hamilton Health Sciences Corporation100 enrolled3 locationsNCT06337838
Recruiting
Phase 4

The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery

Acute Kidney Injury (AKI)AnesthesiaMyocardial Injury After Noncardiac Surgery (MINS)+4 more
University of California, San Francisco18,000 enrolled10 locationsNCT06802224
Recruiting
Not Applicable

Continuous Veno-venous Hemodialysis and Continuous Veno-venous Hemodiafiltration on Urea Reduction Rate in Intensive Care Patient

Continuous renal replacement therapyAcute Kidney InjuryIntensive Care Unit
Centre Hospitalier Universitaire de Nīmes80 enrolled1 locationNCT06369064
Recruiting

Prognostic Value of Novel Biomarkers on Adverse Renal Outcomes in High-Risk Cardiac Surgery Patients

Cardiac Surgery associated Acute kidney injuryCritical Illness
Guowei Tu1,491 enrolled2 locationsNCT07418242
Recruiting
Phase 3

Ultra-Low Contrast Angiography in AKI

Acute Kidney Injury
Tulane University32 enrolled2 locationsNCT05906758
Recruiting

Postoperative Acute Kidney Injury in Children Undergoing Major Non-cardiac Surgery

Acute Kidney Injury
Uppsala University2,000 enrolled13 locationsNCT07351149
Recruiting

QUELIMMUNE (SCD-PED) PediAtric SurVeillance REgistry

Acute Kidney InjuryAcute Kidney Injury Due to Sepsis
SeaStar Medical50 enrolled15 locationsNCT06517810
Recruiting
Not Applicable

UPTAKE - Virtual Care: Virtual Home Hospital With Remote Monitoring to Reduce Acute Care Hospitalization

Acute Kidney Injury
University of Calgary354 enrolled2 locationsNCT06537453
Recruiting
Not Applicable

Effects of Sedation, TEmperature and Pressure After Cardiac Arrest and REsuscitation on Major Adverse Kidney Events (STEPCARE-MAKE)

TemperatureBlood PressureCardiac Arrest (CA)+9 more
Helsinki University Central Hospital3,500 enrolled52 locationsNCT07579390