RecruitingNCT06611280

Deuterium Metabolic Imaging in People with Multiple Sclerosis


Sponsor

University of Aarhus

Enrollment

20 participants

Start Date

Oct 1, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this case-control study is to investigate glucose brain metabolism in people with multiple sclerosis and age- and sex-matched healthy controls. The main questions it aims to answer are: * How does brain glucose metabolism in people with multiple sclerosis compare to age- and sex-matched healthy controls? * How is the brain glucose metabolism of people with multiple sclerosis associated with disease severity? Participants will come in for testing lasting approximately three hours and undergo deuterium metabolic imaging, physical function test, cognitive function test, and answer survey.


Eligibility

Min Age: 18 YearsMax Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This study uses a special type of MRI scan called Deuterium Metabolic Imaging to look at how the brain uses energy in people with multiple sclerosis (MS). Researchers want to understand if this new scanning method can detect changes in brain metabolism that standard MRI scans miss. **You may be eligible if...** - You are between 18 and 60 years old - You have been diagnosed with relapsing-remitting multiple sclerosis (RRMS) **You may NOT be eligible if...** - You have a pacemaker, neurostimulator, or metal implants in your body - You experience severe claustrophobia (fear of enclosed spaces) - Your body circumference (including arms) is greater than 160 cm - You are pregnant - You have another serious neurological, psychiatric, or systemic disease such as diabetes - You are currently participating in another clinical drug trial Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERNo Interventions

No delivered intervention.


Locations(1)

Aarhus University

Aarhus C, Denmark

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NCT06611280


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