RecruitingNot ApplicableNCT07376772

Wearable Focal Vibration Therapy on Upper Extremity Function of People With Multiple Sclerosis: A Pilot Study

Feasibility, Preliminary Efficacy, and User Perspective Usability of Wearable Focal Vibration Therapy on Upper Extremity Function of People With Multiple Sclerosis: A Pilot Study

Sponsor

University of Florida

Enrollment

15 participants

Start Date

Mar 4, 2026

Study Type

INTERVENTIONAL

Conditions

Multiple Sclerosis (MS) - Relapsing-remitting Upper Extremity Dysfunction

Summary

This pilot mixed-method study will evaluate the feasibility, preliminary efficacy, and user experience of a home-based wearable Focal Vibration Therapy (FVT) intervention for improving upper extremity (UEx) function in people with multiple sclerosis (MS). Fifteen adults with relapsing-remitting MS (PRMS) and self-reported UEx impairments will participate in a 4-week FVT program using MyovoltTM wearable FVT devices applied to arm muscles.

Eligibility

Min Age: 18 YearsMax Age: 100 Years

Plain Language Summary

Simplified for easier understanding

This pilot study investigates whether a wearable device that delivers gentle vibrations to the arm can help improve hand and arm function in people with relapsing-remitting multiple sclerosis (MS). **You may be eligible if...** - You are 18 or older - You have a confirmed diagnosis of relapsing-remitting MS - You have not had a relapse or worsening of MS symptoms in the last 6 months - You have weakness, spasticity, or reduced arm or hand function related to MS - Your MS treatment has been stable for at least 4 weeks - You are fluent enough in English to participate in interviews and follow instructions - You are able to come into the laboratory for assessments **You may NOT be eligible if...** - You have significant cognitive impairment - You have another neurological or psychiatric condition affecting your arms (such as stroke or severe carpal tunnel syndrome) - You have unstable heart disease or a pacemaker - You have epilepsy, pregnancy, severe osteoporosis, or other contraindications to vibration therapy Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEwearable focal vibration therapy

The focal vibration intervention will be delivered using a modified MyoVolt wearable vibration therapy device. Each MyoVolt vibration device will be assigned to a single participant for individual use only and will be clearly labeled with a unique study ID. Devices will be distributed during the baseline training session and returned at the end of the study. To prevent unauthorized use: * Participants will receive training on the appropriate use and safe handling of the device. * Each device will be stored by the participant in their home in a designated area, along with written instructions and contact information in case of any issues. * The device operates only via a linked smartphone app. This will restrict unauthorized users from easily accessing or operating the device. * Participants will be instructed not to allow others to use the device and to report any device malfunction, loss, or suspected misuse immediately to the research team.