RecruitingNot ApplicableNCT06611579

Clinical Study of the inQB8 TTVR System (The MonarQ Study)

A Clinical Study of the inQB8 Transcatheter Tricuspid Valve Replacement System


Sponsor

inQB8 Medical Technologies, LLC

Enrollment

50 participants

Start Date

Jun 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Prospective, multi-center study to assess safety and performance of the inQB8 MonarQ Tricuspid Valve Replacement System.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Anatomically suitable for the MonarQ TTVR System
  • Symptomatic, tricuspid regurgitation (TR) that is severe or greater
  • Adequately treated for heart failure based upon medical standards
  • Hemodynamically stable

Exclusion Criteria4

  • Need for emergent or urgent surgery for any reason, any planned cardiac surgery within the next 12 months (365 days), or any planned percutaneous cardiac procedure within the next 90 days
  • Refractory Heart Failure (HF) that requires or required advanced intervention
  • Any condition, in the opinion of the investigator, making it unlikely the patient will be able to complete all protocol procedures and follow-up.
  • Currently participating in another investigational biologic, drug or device study

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Interventions

DEVICETranscatheter Tricuspid Valve Replacement

Replacement of the tricuspid valve using a transcatheter approach


Locations(8)

Cedars-Sinai Medical Center

Los Angeles, California, United States

Los Robles Hosptial and Medical Center

Thousand Oaks, California, United States

Piedmont Atlanta Hospital

Atlanta, Georgia, United States

North Shore University Hospital

Manhasset, New York, United States

Penn Presbyterian Medical Center

Philadelphia, Pennsylvania, United States

Baylor Heart Hospital

Plano, Texas, United States

AZ Sint-Jan Brugge AV

Bruges, Belgium

St. Michael's Hospital

Toronto, Ontario, Canada

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NCT06611579


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