RecruitingNCT07267117

Cohort Observing Mechanisms, Progression and Sequelae of Valvular Heart Disease

Cohort Observing Mechanisms, Progression and Sequelae of Valvular Heart Disease (VALVE-COMPASS)

Sponsor

Second Affiliated Hospital, School of Medicine, Zhejiang University

Enrollment

10,000 participants

Start Date

Jun 1, 2025

Study Type

OBSERVATIONAL

Conditions

Aortic Valve Disease Heart Valve Disease Tricuspid Valve Regurgitation Aortic Valve Stenosis Aortic Valve Regurgitation Tricuspid Valve Disease Transcatheter Aortic Valve Replacement (TAVR)Mitral Valve Stenosis Mitral Valve Disease Mitral Valve (MV) Regurgitation Pulmonary Valve Disease Transcatheter Valve Replacement Transcatheter Pulmonary Valve Replacement (TPVR)Transcatheter Edge-to-edge Repair

Summary

The objective of this study is to evaluate and predict the progression of moderate cardiac valve stenosis and regurgitation using clinical, biological, echocardiographic, computed tomography (CT), and magnetic resonance imaging (MRI) data. Additionally, the study aims to analyze the potential impact of device-based interventions, pharmacological therapy, and lifestyle modifications on disease progression.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a new treatment for people with aortic valve disease, aortic valve regurgitation, and other related conditions. The study is currently recruiting participants at 15 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(15)

Fujian Provincial Hospital, Affiliated to Fuzhou University

Fuzhou, Fujian, China

Renmin Hospital of Wuhan University

Wuhan, Hubei, China

Xiangya Hospital of Central South University

Changsha, Hunan, China

Second Xiangya Hospital of Central South University

Changsha, Hunan, China

The General Hospital of Northern Theater Command

Shenyang, Liaoning, China

The First Affiliated Hospital of Air Force Medicial University

Xi'an, Shaanxi, China

Affiliated Hospital of Qingdao University

Qingdao, Shandong, China

Huaxi Hospital

Chengdu, Sichuan, China

People's Hospital of Xinjiang Uygur Autonomous Region

Ürümqi, Xinjiang, China

Fuwai Yunnan Cardiovascular Hospital

Kunming, Yunnan, China

Second Affiliated Hospital of Zhejiang University, School of Medicine

Hangzhou, Zhejiang, China

Chinese Academy of Medical Sciences, Fuwai Hospital

Beijing, China

Navy General Hospital, Beijing

Beijing, China

Army Medical Center of PLA

Chongqing, China

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Shanghai, China

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

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NCT07267117

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