RecruitingPhase 4NCT06613178

Intravenous Acetaminophen After Cardiac Surgery - Definitive Study

Intravenous Acetaminophen After Cardiac Surgery


Sponsor

McGill University Health Centre/Research Institute of the McGill University Health Centre

Enrollment

1,100 participants

Start Date

Jul 2, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Double blind, double dummy trial of the use of IV acetaminophen versus oral acetaminophen for the prevention of delirium after cardiac surgery. The underlying hypothesis is that better pain control and less use of narcotics will lead to a lower incidence of delirium from day 1 to 7 following cardiac surgery. Other important secondary outcomes are the total use of narcotics, ICU and hospital stay, improved cognitive function at 6 months and 1 year post surgery, NSAID use at each centre and associated NSAID complications.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called acetaminophen for people with post operative delirium, post operative pain, and other related conditions. The study is currently recruiting participants at 8 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGacetaminophen

Patient receive IV acetaminophen (and oral placebo) or placebo IV acetaminophen and oral acetaminophen. All drugs are blinded


Locations(8)

University of British Columbia

Vancouver, British Columbia, Canada

University of Manitoba

Winnipeg, Manitoba, Canada

Trillium Health Centre

Mississagua, Ontario, Canada

University of Ottawa

Ottawa, Ontario, Canada

Sunnybroook Health Centre

Toronto, Ontario, Canada

McGill Universtiy Health Centre

Montreal, Quebec, Canada

Universite Montreal

Montreal, Quebec, Canada

University of Laval

Québec, Quebec, Canada

View Full Details on ClinicalTrials.gov

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NCT06613178


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