RecruitingNCT06613256

Characterisation of Endothelial Cells in Different Inflammatory Pathologies


Sponsor

Royal Surrey County Hospital NHS Foundation Trust

Enrollment

105 participants

Start Date

Jul 16, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational study is to characterise changes in gene expression in endothelial cells in patients with either sepsis or post major abdominal surgery. The main question we plan to answer is: 'What molecular pathways are differentially expressed during inflammatory pathologies?'


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Endothelial cell biopsy for people with sepsis and vasoplegia. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHEREndothelial cell biopsy

Endothelial cell sample collected from the antecubital fossa of patients. A vein in the antecubital fossa is cannulated with a 20 g valveless cannula. A metal guidewire is then passed into the vessel to collect endothelial cells for analysis


Locations(1)

Royal Surrey NHS Foundation Trust

Guildford, Surrey, United Kingdom

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NCT06613256


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