AdLip: Human Coach-supported Digital/AI Personal Health Assistant to Improve Adherence to Lipid-Lowering Medication
AdLip: Use of Human Coach-supported Digital/AI Personal Health Assistant to Improve Adherence to Lipid-Lowering Medications: a Multi-centre Randomised Controlled Trial
National University of Singapore
450 participants
Jun 10, 2024
INTERVENTIONAL
Conditions
Summary
Investigators hypothesize that the use of a human coach-supported digital/AI personal health assistant (app) will improve adherence to cholesterol-lowering medications (statins with or without ezetimibe) among patients with hyperlipidaemia and suboptimal LDL-C control, when compared to standard care.
Eligibility
Inclusion Criteria6
- Between 21 to 84 years old
- Prescribed statins with or without ezetimibe for hyperlipidaemia.
- Medication non-adherence as defined by the \"Extent to Non-adherence\" sub-scale of the DOSE Non-Adherence Measure), with a score \> 1 (range from 0-15)
- Singapore residents (citizens, permanent residents, or long-term pass holders).
- In possession of a smartphone or tablet with Android or iOS operating systems.
- Have internet access on their mobile devices.
Exclusion Criteria10
- Does not read or understand English. Current use of smartphone medication adherence app(s) that include statins.
- Concurrent use of PCSK9 Inhibitors in addition to statins and/or ezetimibe
- Participation in another study that uses medications that could affect lipid levels
- Severe renal impairment defined as chronic kidney disease stage 4 and above.
- Severe liver disease (Child-Pugh Class C)
- Existing muscular-related complaints or diagnoses which may confound adverse event reporting
- Uncorrected thyroid conditions, especially poorly-controlled hypothyroidism
- Documented psychiatric diagnosis or history of mental illness or deemed as unable to give informed consent.
- Currently pregnant, breastfeeding or expecting to get pregnant during the course of the study (1 year).
- Guarded prognosis with expectant mortality within 12 months or less.
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Interventions
Receive personalised feedback and educational content curated by local clinicians and pharmacists through the CADENCE D-PHA app coupled with six sessions of human coaching on top of usual clinical care for lipid management over 6 months
Locations(2)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06614049