RecruitingNot ApplicableNCT06624046

Circadian Mechanisms, Glucose, and CV Risks in T1D

Circadian Mechanisms of Glycemic Control and Cardiovascular Risk in Adults With Type 1 Diabetes


Sponsor

University of Illinois at Chicago

Enrollment

100 participants

Start Date

Mar 13, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

People with type 1 diabetes are disproportionately affected by cardiovascular disease (CVD). Short and irregular sleep have been associated with cardiovascular risk in this population. Improving sleep regularity has been associated with improved glycemic markers however mechanisms by which improving sleep regularity improves metabolic and cardiovascular health is not known. The investigators propose to conduct a mechanistic study using a sleep stability manipulation. This proposal will advance the understanding of mechanisms by which improving sleep regularity influences glycemic control and cardiovascular risk in T1D.


Eligibility

Min Age: 18 YearsMax Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This study investigates how irregular sleep patterns affect blood sugar control and heart health in adults with type 1 diabetes. Researchers believe that improving sleep consistency could reduce heart disease risk in this population, and this study will test a sleep-improvement intervention. **You may be eligible if...** - You are between 18 and 50 years old - You have been diagnosed with type 1 diabetes for at least one year - Your sleep schedule varies by 1 hour or more per week (irregular sleep) - You want to improve your sleep and own a smartphone (Android or iPhone) **You may NOT be eligible if...** - Your HbA1c (a 3-month blood sugar average) is 10% or above - You have significant insomnia (Insomnia Severity Index score 15 or above) - You have restless leg syndrome - You have had a severe low blood sugar episode (seizure, loss of consciousness, or ER visit) in the past 6 months - You work rotating or night shifts, or regularly sleep past 3 AM - You currently take sleep medications Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALSleep stability intervention

The sleep stability intervention will consist of three theory-based intervention components our team has developed and used in prior interventions: 1) self-monitoring using a wearable sleep tracker (Fitbit). This is well-liked by participants and increases awareness of their sleep goals. 2) Accountability coaching via weekly check-ins and daily monitoring of participants' wearable sleep tracking data and a coaching protocol.


Locations(1)

University of Illinois Chicago

Chicago, Illinois, United States

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NCT06624046


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