Addiction Potential of Very Low Nicotine Filtered Little Cigars
Ohio State University Comprehensive Cancer Center
50 participants
Feb 13, 2025
INTERVENTIONAL
Conditions
Summary
The goal of this clinical trial is to learn how reducing the nicotine content in filtered little cigars can affect the the use of these cigars and lung health in current adult filtered little cigar users. The main question\[s\] it aims to answer are: Are puffing behaviors, appeal/satisfaction, craving suppression, pharmacokinetic effects, and demand similar between the regular cigars smoked by participants, normal nicotine study cigars and very low nicotine study cigars? Are health effects and toxicant exposure similar between the regular cigars smoked by participants, normal nicotine study cigars and very low nicotine study cigars? Participants will attend three study visits at OSU. Each visit would last up to 4 hours. During visits, they will * fill several surveys * provide blood samples * perform breathing tests * complete smoking sessions using either their own cigars or the study cigars.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
Participants will smoke a very low nicotine content filtered little cigar containing 0.50mg nicotine per gram of tobacco
Participants will smoke a normal nicotine content filtered little cigar containing 5.17mg nicotine per gram of tobacco
Participants will smoke their usual brand filtered little cigar
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06630728