RecruitingPhase 4NCT06630728

Addiction Potential of Very Low Nicotine Filtered Little Cigars


Sponsor

Ohio State University Comprehensive Cancer Center

Enrollment

50 participants

Start Date

Feb 13, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to learn how reducing the nicotine content in filtered little cigars can affect the the use of these cigars and lung health in current adult filtered little cigar users. The main question\[s\] it aims to answer are: Are puffing behaviors, appeal/satisfaction, craving suppression, pharmacokinetic effects, and demand similar between the regular cigars smoked by participants, normal nicotine study cigars and very low nicotine study cigars? Are health effects and toxicant exposure similar between the regular cigars smoked by participants, normal nicotine study cigars and very low nicotine study cigars? Participants will attend three study visits at OSU. Each visit would last up to 4 hours. During visits, they will * fill several surveys * provide blood samples * perform breathing tests * complete smoking sessions using either their own cigars or the study cigars.


Eligibility

Min Age: 21 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Normal nicotine content cigar, a drug called Reduced Nicotine Content Cigars, and others for people with smoking (tobacco) addiction. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGReduced Nicotine Content Cigars

Participants will smoke a very low nicotine content filtered little cigar containing 0.50mg nicotine per gram of tobacco

DRUGNormal nicotine content cigar

Participants will smoke a normal nicotine content filtered little cigar containing 5.17mg nicotine per gram of tobacco

DRUGUsual brand cigar

Participants will smoke their usual brand filtered little cigar


Locations(1)

The Ohio State University

Columbus, Ohio, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06630728


Related Trials