Oklahoma Study of Native American Pain Risk IV: Smoking Cessation and Pain
Can Smoking Cessation Improve Physiological Markers of Chronic Pain Risk in Native American Smokers?: A Pilot Feasibility Study
University of Oklahoma
150 participants
Sep 1, 2025
INTERVENTIONAL
Conditions
Summary
The goal of this pilot study is to assess whether 4-weeks of verified smoking abstinence following financial incentive treatment for smoking cessation improves physiological markers of chronic pain risk in adult Native American smokers. The main aims to answer are: 1. Determine study feasibility. 2. Obtain effect sizes for changes in pain amplification and pain inhibition in abstinent vs non-abstinent Native Americans. 3. Obtain effect sizes for variables in the conceptual model of the Native American smoking-pain relationship.
Eligibility
Inclusion Criteria4
- Self-identify as Native American/American Indian
- Currently daily smoker
- Own a smartphone with a data plan
- Ability to speak and read English
Exclusion Criteria9
- \>18 years of age
- Currently pregnant
- Self-reported history of heart disease or heart attack
- Angina, arrhythmias, hypertension, heart disease
- Current chronic pain
- Pepper allergy
- Inability to speak English
- Current psychosis (assessed by Psychosis Screening Questionnaire)
- Serious cognitive impairment (assessed by \<20 score on the Montreal Cognitive Assessment \[MoCA\])
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Interventions
Investigators will provide financial incentives for biochemically verified abstinence at 4 weeks following treatment. This incentive is consistent with recent research using macro-level financial incentives and incorporates both short-term and long-term incentives to shape behavior.
Locations(1)
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NCT07080788