Study SOLACE SEPSIS

This study, called SOLACE SEPSIS, is testing a specific fluid resuscitation approach for people in septic shock — a life-threatening condition where the body's response to infection causes organ failure. The study focuses on whether carefully guided fluid management using ultrasound monitoring can improve outcomes for critically ill patients. **You may be eligible if...** - You are between 18 and 90 years old - You are in septic shock (your body is severely infected and you need blood pressure support with medication, and your blood lactate is elevated) - You need fluid treatment and show signs of poor circulation (such as delayed capillary refill, low urine output, or poor mental alertness) - Testing shows your heart is likely to respond well to fluids **You may NOT be eligible if...** - Your heart cannot be visualized by chest ultrasound - You weigh more than 160 kg - Your blood sodium is dangerously high - You have cardiac tamponade (fluid around the heart), severe valve disease, or life-threatening arrhythmia - You are expected to die before the study protocol can be completed - You need emergency dialysis within 2 hours - You have severe liver failure or active pregnancy Talk to your doctor to see if this trial is right for you.