RecruitingNot ApplicableNCT06640101

Effects of Inspiratory Muscle Training on Stroke Rehabilitation Outcomes

Effect of Inspiratory Muscle Training on Respiratory Function, Diaphragm Thickness, Balance Control, Exercise Capacity and Quality of Life in People After Stroke: a Randomized Controlled Trial

Sponsor

Hong Kong Metropolitan University

Enrollment

84 participants

Start Date

Feb 21, 2025

Study Type

INTERVENTIONAL

Conditions

Stroke

Summary

This study is designed to explore the effects of a 4-week protocol of inspiratory muscle training (IMT) at 50% maximum inspiratory pressure (MIP) on respiratory function, diaphragm thickness, balance control, exercise capacity, and quality of life in people after stroke. To ascertain the effect of IMT on the relationship between diaphragm muscle contraction and activation of other trunk muscles, this study also explores whether any effect of the 4-week IMT protocol on balance control is associated with changes in the anticipatory posture adjustments (APAs) time - the onset time of postural muscles during a required task (e.g., the rapid shoulder flexion test).

Eligibility

Min Age: 40 YearsMax Age: 80 Years

Inclusion Criteria10

Age ≥ 40 years and < 80 years;
breathing spontaneously;
clinically diagnosed with ischemic and/or haemorrhagic stroke;
duration of stroke from onset falls within 1 month to 12 months after diagnosis;
no thoracic or abdominal surgery within the last 6 months;
able to understand and follow verbal instructions;
no facial palsy, or mild facial palsy without limitation of labial occlusion;
able to maintain a resting sitting posture without feet support for at least 30 seconds;
no cognitive impairment (Montreal Cognitive Assessment (MoCA) score ≥ 26);
able to independently walk at least 10 meters with or without an assistive device.

Exclusion Criteria6

acute myocardial infarction or acute heart failure;
acute pain in any part of the body;
with respiratory illness or positive clinical signs of impaired respiratory function (such as shortness of breath, hypoxemia, chronic cough and sputum retention);
with chronic cardiovascular dysfunction;
Trunk Impairment Scale (TIS) score ≥ 20.
patient with a nasal feeding tube, tracheal tube and/or any condition that prevents the measurement or the implementation of the study procedure.

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Interventions

OTHERsham IMT

with 10% maximum inspiratory pressure (MIP) as the training intensity, IMT will be conducted on a stable surface

OTHERIMT-stable group (sitting on a stable surface)

50% MIP as the training intensity, IMT will be conducted while sitting on a stable surface

OTHERIMT-unstable group (sitting on an unstable surface)

50% MIP as the training intensity, IMT will be conducted while sitting on an unstable surface

OTHERConventional treatment

Participants in all groups will receive a standardised conventional rehabilitation protocol. It includes limb range of motion, muscle tone reduction, strengthening and endurance of limb muscles, transfer skills, task-directed movements, general gait training, and activities of daily living training.