RecruitingNot ApplicableNCT06641011

This Study Aims to Evaluate the Effect of Rinsing Off or Blot-drying Silver Fluoride on the Retention of Subsequently-applied Resin- and Glass Ionomer-based Fissure Sealants in Permanent Molars Affected by Molar-Incisor Hypomineralization.

The Effect of Rinsing Off or Blot-drying Silver Fluoride on the Retention of Subsequently-applied Resin- and Glass Ionomer-based Fissure Sealants in Permanent Molars Affected by Molar-Incisor Hypomineralization.


Sponsor

Hacettepe University

Enrollment

104 participants

Start Date

Jul 31, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The aim of this study is three-fold: 1. To evaluate the clinical performance of glass ionomer fissure sealants and resin fissure sealants when placed immediately after or one week following the application of silver fluoride on permanent molars affected by Molar-Incisor Hypomineralization in high caries-risk children. 2. To compare the effects of rinsing off the silver fluoride or not rinsing it off (blot-drying with cotton pellet) on sealant retention when the sealant is placed immediately after silver fluoride application, and 3. To measure the desensitizing effect of fissure sealant application following silver fluoride treatment on hypersensitive MIH molars.


Eligibility

Min Age: 6 YearsMax Age: 14 Years

Inclusion Criteria4

  • Patients and their parents who consent to participate and have signed the informed consent form.
  • Patients with at least one permanent molar diagnosed with molar incisor hypomineralization based on EAPD guidelines.
  • Fully erupted teeth with ICDAS I or II lesions that necessitate the application of fissure sealants.
  • Teeth displaying demarcated opacities on the occlusal surface and at least one additional surface.

Exclusion Criteria5

  • Teeth that have existing restorations or cavities.
  • Patients currently receiving orthodontic treatment.
  • Patients who are uncooperative during dental procedures.
  • Teeth affected by dental fluorosis or enamel defects associated with specific syndromes.
  • Children with systemic conditions requiring ongoing medication.

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Interventions

DEVICEImmediate restoration (resin- based) after blot-drying silver fluoride application

Blot-drying silver fluoride with cotton pellet followed by resin-based fissure sealant

DEVICEImmediate restoration (GI- based) after blot-drying silver fluoride application

Blot-drying silver fluoride with cotton pellet followed by glass ionomer-based fissure sealant

DEVICEImmediate restoration (Resin based) after rinsing silver fluoride application

Rinsing silver fluoride off followed by resin-based fissure sealant

DEVICEImmediate restoration (GIC) after rinsing silver fluoride application

Rinsing silver fluoride off and blot-drying of fissures followed by glass ionomer-based fissure sealant

DEVICEResin based fissure sealant restoration one week after silver fluoride (AgF) application

Resin based fissure sealant restoration one week after silver fluoride (AgF) application

DEVICEGI- based fissure sealant restoration one week after silver fluoride (AgF) application

GI- based fissure sealant restoration one week after silver fluoride (AgF) application


Locations(1)

Hacettepe University Faculty of Dentistry, Department of Pediatric Dentistry

Ankara, Turkey (Türkiye)

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NCT06641011


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