RecruitingNot ApplicableNCT06642883

Evaluation of ProLife 10 FORTE on Gut Microbiota Composition in UC Patients

Evaluation of the Effects of 10-strain Probiotic (ProLife 10 FORTE) on Gut Microbiota Composition in Patients Presenting with Ulcerative Colitis During the Remission Phase


Sponsor

University of Padova

Enrollment

70 participants

Start Date

May 15, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This clinical trial aims to learn if the probiotic Prolife 10 Forte could improve the Gut Microbiota composition of Ulcerative colitis patients during the remission phase. The main questions it seeks to answer are: * Does Prolife 10 Forte improve the microbiota composition in patients with Ulcerative colitis? * Is it possible to highlight the variation in microbial pathways? * What clinical parameters vary and are associated with changes in the gut microbiota? Researchers will compare Prolife 10 Forte to a placebo (a look-alike substance containing no drug) to see if the probiotics improve microbiota. Participants will: * Take 1 vial/day of Prolife 10 Forte /Placebo for 60 days. * Visit the clinic two times for checkups, Questionaire and tests


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This trial is testing whether a specific probiotic supplement (ProLife 10 FORTE) can positively change the gut bacteria in people with ulcerative colitis (UC) that is currently in remission. **You may be eligible if...** - You have been diagnosed with ulcerative colitis confirmed by clinical, endoscopic, and biopsy findings - Your UC is currently in remission - You are between 18 and 75 years old - You are able to fully participate in all aspects of the trial **You may NOT be eligible if...** - Your UC is currently active - You have Crohn's disease or other types of colitis - You have tested positive for C. difficile (a gut infection) - You are pregnant - You are allergic to soy or fructose - You have used antibiotics or probiotics within 10 days before the study starts Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DIETARY_SUPPLEMENTProlife

randomized in a 1:1 ratio to treatment :1 vial/day for 60 days.

DIETARY_SUPPLEMENTPlacebo

Placebo: 1 vial/day for 60 days.


Locations(1)

Edoardo Vincenzo Savarino

Padua, Padua, Italy

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06642883


Related Trials