RecruitingNot ApplicableNCT06646172

Liposomal Bupivacaine and Bupivacaine for TTMPB in Median Sternotomy

Liposomal Bupivacaine and Bupivacaine Alone Transverse Thoracic Muscle Plane Blocks in Median Sternotomy: a Prospective, Single-blind, Randomized Controlled Study

Sponsor

Tongji Hospital

Enrollment

38 participants

Start Date

Oct 24, 2024

Study Type

INTERVENTIONAL

Conditions

Median Sternotomy

Summary

In light of the ongoing controversy surrounding the efficacy of bupivacaine liposomes, our study was designed to investigate, for the first time, the differential postoperative analgesic effects between bupivacaine liposomes combined with bupivacaine hydrochloride and bupivacaine hydrochloride alone in transverse thoracic muscle plane block treatment. The aim is to provide evidence-based medical guidance for drug selection in regional block local anesthesia.

Eligibility

Min Age: 18 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Transverse thoracic muscle plane block (TTMPB) using bupivacaine hydrochloride and a procedure called Transverse thoracic muscle plane block (TTMPB) using liposomal bupivacaine and bupivacaine mixture for people with median sternotomy. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 90 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDURETransverse thoracic muscle plane block (TTMPB) using liposomal bupivacaine and bupivacaine mixture

Liposomal bupivacaine and bupivacaine mixture were used for transverse thoracic muscle plane block (TTMPB) in experimental group.

PROCEDURETransverse thoracic muscle plane block (TTMPB) using bupivacaine hydrochloride

Bupivacaine hydrochloride was used for transverse thoracic muscle plane block (TTMPB) in active control group.

Locations(1)

Tianzhu Liu

Wuhan, Hubei, China

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NCT06646172

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