Robot-assisted Training
Evaluation of a Portable Isokinetic Knee Training Device for Quadriceps Rehabilitation in Children With SMA
Peking University Third Hospital
13 participants
Feb 25, 2025
INTERVENTIONAL
Conditions
Summary
The goal of this clinical trial is to evaluate the long-term effects of isokinetic rehabilitation training in patients with spinal muscular atrophy (SMA). The main question it aims to answer is: • Does isokinetic training at fixed angular velocity improve muscle strength and functional recovery in SMA patients? Participants will: * Perform isokinetic training using a portable device with a fixed angular velocity. * Undergo long-term rehabilitation sessions, with assessments of muscle strength and overall functional improvement over the training period.
Eligibility
Inclusion Criteria2
- Age range: 6-12 years old.
- Diagnosed with Type II Spinal Muscular Atrophy (SMA).
Exclusion Criteria4
- Participants with severe comorbidities, implanted medical devices preventing MRI or claustrophobia were excluded from the study.
- Refusal to provide informed consent or inability to complete the entire study protocol, among other factors;
- Uncontrolled hypertension (systolic blood pressure ≥160 mmHg and/or diastolic blood pressure ≥95 mmHg) or congestive heart failure classified as New York Heart Association (NYHA) Class III or IV;
- Cognitively impaired or unable to comprehend the requirements of study participation.
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Interventions
A child with SMA will use a wearable isokinetic training robot to train the knee joint for three stages. ( Stage 1: 1.5 months=30 sessions; Stage 2 (follow up): 1.5 months=18 sessions, Stage 3(follow up) = 0 session)
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06648486