RecruitingNot ApplicableNCT07488338

HABIT-ILE + FST in Children With SMA: Preliminary Effectiveness

Feasibility and Preliminary Effectiveness of HABIT-ILE + Functional Strength Training in Children With Spinal Muscular Atrophy (SMA): a Prospective Single-group Intervention Trial.


Sponsor

Teachers College, Columbia University

Enrollment

20 participants

Start Date

Mar 15, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This single-arm pilot study will assess the preliminary effectiveness of an intensive motor skill intervention (HABIT-ILE) combined with functional strength training (FST) in children with SMA who are receiving disease-modifying therapies. Participants will attend a HABIT-ILE + FST summer camp for 6 hours per day over a 3-week period, totaling 90 hours of training.


Eligibility

Min Age: 5 YearsMax Age: 17 Years

Inclusion Criteria7

  • Have a confirmed SMA diagnosis
  • Be 5-17 years old
  • Complete all pre- and post-intervention assessments
  • Understand and speak English
  • Follow instructions without major cognitive or behavioral issues
  • Have received a stable disease-modifying therapy (DMT) dose for ≥6 months
  • Be classified as a sitter or walker (SMA type 2 or 3) with supported standing ability (score ≥1 on Item 18 of the HFMSE) without KAFOs, AFOs, or external standing devices

Exclusion Criteria3

  • Orthopedic surgery within the past year
  • New pharmaceutical treatment during the study
  • Concurrent participation in another clinical trial

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Interventions

OTHERCombined Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) + functional strength training (FST)

Goal-directed, task-specific training for both the upper and lower extremity, and postural control with targeted strengthening exercises to enhance motor control and facilitate the achievement of functional goals


Locations(1)

Center for Cerebral Palsy Research, Teachers College, Columbia University

New York, New York, United States

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NCT07488338


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