RecruitingNot ApplicableNCT06652425

Acute Effects of Cold Exposure on Cardiovascular System

Acute Effects of Cold Exposure on Cardiovascular System and Potential Mechanism in Healthy Young Adults: A Randomized Controlled Study

Sponsor

Fudan University

Enrollment

40 participants

Start Date

Oct 16, 2024

Study Type

INTERVENTIONAL

Conditions

Cardiovascular System

Summary

This is a randomized controlled human exposure crossover study. Investigators aim to assess the acute effects of low temperature exposure on cardiovascular system and the underlying mechanisms.

Eligibility

Min Age: 18 YearsMax Age: 30 Years

Inclusion Criteria5

Living in Shanghai during the study period;
Body mass index \> 18.5 and ≤ 28;
Right-handed;
Receiving or having received higher education;
With the ability to read and understand Chinese smoothly.

Exclusion Criteria10

Smoking and alcohol abuse;
Current drug and dietary supplements intake;
Subjects with allergic diseases, such as allergic rhinitis, allergic asthma, and atopy;
Subjects with cardiovascular diseases, such as congenital heart disease, pulmonary heart disease, and hypertension;
Subjects with respiratory diseases, such as asthma, chronic bronchitis, and chronic obstructive pulmonary disease;
Subjects with chronic diseases, such as diabetes, chronic hepatitis, and kidney disease;
Subjects who have a history of major surgery due to cardiovascular, cerebrovascular, respiratory, or neurological diseases;
Subjects with neurologic disorders, such as stroke, traumatic brain injury, epilepsy, and schizophrenia;
Abnormal spirometry (FEV1 and FVC ≤ 75% of predicted and FEV1/FVC ≤ 0.65);
Subjects with color vision disabilities.

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