RecruitingNot ApplicableNCT07501923

The Effects of Daytime, Nighttime, and Combined Heat Exposure on Human Health

Randomized Controlled Crossover Trial on the Effects of Daytime, Nighttime, and Combined Heat Exposure on Human Health

Sponsor

Jian Cheng

Enrollment

35 participants

Start Date

Jun 1, 2025

Study Type

INTERVENTIONAL

Conditions

Metabolism Changes Cardiovascular System Psychology Functional Behavior Respiratory System

Summary

Assess the acute effects of high-temperature exposure (including both daytime and nighttime conditions) on multiple physiological and psychological indicators, including cardiovascular, respiratory, neuropsychiatric, and metabolic functions, along with their potential mechanisms.

Eligibility

Min Age: 18 YearsMax Age: 30 Years

Inclusion Criteria4

Age 18-30;
In good health, with no history of cardiovascular disease, respiratory disease, diabetes, endocrine disorders, neurological or psychiatric conditions;
No smoking or alcohol addiction, no history of substance abuse;
No prior history of particular sensitivity to high-temperature environments.

Exclusion Criteria5

Individuals who have experienced fever, colds, infectious diseases, or significant physical trauma within two weeks prior to the high-temperature test;
Individuals currently using medications that may affect psychological, cognitive, cardiovascular, or respiratory functions;
Pregnant women and lactating females;
Participants shall not be scheduled to participate during menstruation;
Individuals with a history of fainting or severe discomfort caused by high temperatures.

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Interventions

OTHERDaytime or Nighttime High-Temperature Exposure

Daytime Exposure Phase: The exposure group will be exposed to high temperature (32#) in a chamber for about 8 hours, resting during the whole periods Nighttime Exposure Phase: The exposure group will be exposed to high temperature (30#) in a chamber for about 8 hours, resting during the whole periods Day-Night Combined Exposure Phase: The exposure group will be exposed continuously to high temperatures during the day and night

OTHERDaytime and nighttime neutral temperature exposure

Daytime Exposure Phase: The control group will be exposed to neutraltemperature (26#) in a chamber for about 8 hours, resting during the whole periods Nighttime Exposure Phase: The control group will be exposed to neutral temperature (26#) in a chamber for about 8 hours, resting during the whole periods Day-Night Combined Exposure Phase: The control group will be exposed continuously to neutraltemperatures during the day and night