A Multiple Case Study of Schema Therapy for Difficult-to-treat Depression- DEPRE-ST*Case
A Multiple Case Study of Schema Therapy for Difficult-to-treat Depression - DEPRE-ST*Case
Region of Southern Denmark
3 participants
Nov 6, 2024
INTERVENTIONAL
Conditions
Summary
This clinical multiple case study seeks to expand the knowledge of how schema therapy could function as an intervention for difficult-to-treat depression. The study will explore in depth the course of a 30 session treatment with schema therapy conducted over approximately one year on three individual patients at two different psychiatric treatment sites. Together, the data from this study will inform about the feasibility of schema therapy for difficult-to-treat depression as well as form the base for recommendations in adapting schema therapy for this particular patient group.
Eligibility
Inclusion Criteria4
- Participants have at the time of inclusion been referred to treatment for depression as a primary diagnosis in a psychiatric clinic
- Participants should meet the diagnosis of chronic or treatment-resistant depression as follows:
- Clinical major depression as measured by the M.I.N.I. diagnostic interview: duration minimum two years OR persistent after = 2 trials of antidepressants from different classes, in an adequate dosage and time period (= 4 weeks) OR moderate treatment resistance as measured on the MSM-scale, score \> 6
- Minimum a score of 9 points on the Hamilton Rating Scale for Depression 6 (HAMD-6), corresponding to moderate to severe depression
Exclusion Criteria6
- Alcohol or substance abuse
- Bipolar or psychotic disorder
- Acute suicidal risk
- Mental disability (estimated IQ \< 70)
- Non-Danish speaker
- Known to be pregnant at time of inclusion
Interventions
Schema therapy is a form of psychotherapy invented to address more complex clinical cases. It consists of elements from Cognitive Behavioral Therapy as well as psychodynamic, emotion-focused and gestalt therapies, with a distinct focus on experiential interventions. A therapy manual was developed for use in this study.
Locations(2)
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NCT06655623