Peripheral Drivers of Heart Failure Progression - The Prospective PEDAL-HF Study
University of Leipzig
1,000 participants
Nov 28, 2024
INTERVENTIONAL
Conditions
Summary
PEDAL-HF is a registry-based randomized prospective multicenter study. The investigators plan to include 1000 patients who were recently admitted with acute decompensated heart failure at five tertiary heart clinics in Germany. For the randomised part, 750 patients will be randomized to care within a heart failure network or usual care. The primary endpoint of the randomized trial is change in NT-proBNP from baseline to 6 months of follow-up. All patients (randomized or not) will be followed for two years.
Eligibility
Inclusion Criteria2
- Patients admitted to the participating study centres with acute decompensated heart failure (ADHF), defined as clinical signs and/or symptoms of heart failure
- objective structural cardiac abnormalitites according to the ESC criteria.
Exclusion Criteria4
- Age <18 years
- pregnancy
- any condition interfering with the informed consent process
- patients placed in an institution by official or court order
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Interventions
Patients will receive three visits within the first three months after randomization for improving heart failure therapy at a cardiologist or the outpatient heart failure clinic
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06656832