RecruitingNot ApplicableNCT06660446

Exercise During Chemotherapy Treatment As Adjuvant Program in Patients with Lymphoma: EDONOLA Study.

Ejercicio Físico Durante El Tratamiento De Quimioterapia Como Programa Adyuvante En Pacientes Con Linfoma: Estudio EDONOLA


Sponsor

Biogipuzkoa Health Research Institute

Enrollment

180 participants

Start Date

Oct 8, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

In people diagnosed with lymphoma receiving immunochemotherapy treatment, a combined exercise intervention, as opposed to the general recommendations, will achieve: 1.Improve cardiorespiratory fitness, strength, psychological well-being and quality of life. //2.Reduce fatigue//3.Reduce frailty There is an association between some biological biomarkers with physical capacity and frailty.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study (EDONOLA) examines whether a structured exercise program — two 80-minute sessions per week for 20 weeks — during chemotherapy helps people with lymphoma feel better, tolerate treatment, and recover faster. Participants use a mobile app to track their activity. **You may be eligible if...** - You are 18 or older with a confirmed diagnosis of lymphoma requiring chemotherapy - You can commit to two exercise sessions per week for 20 weeks - You have a mobile phone and are willing to download an activity tracking app - Your performance status is ECOG 2 or better - Your expected survival is over 12 months **You may NOT be eligible if...** - You have a contraindication to moderate-to-high intensity exercise - You have a serious heart, lung, or musculoskeletal condition that limits exercise - You are already meeting World Health Organization physical activity guidelines (very active) - Your cancer has spread to the brain or central nervous system - Your treatment is immunotherapy only (no chemotherapy) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERExercise

The lymphoma unit of the Donostia University Hospital (HUD) is part of the Onkofrail project that analyzes the impact of a physical activity in older cancer patients. The Onkofrail study has included everything type of solid tumors and very diverse treatments, which is a limitation methodology that could condition the analysis of the results. Therefore, the need of proposing a new PE project in a homogeneous population such as that of people with lymphoma, the most prevalent hemopathy in our environment, which has a great survival, but present important adverse effects secondary to treatment systemic.


Locations(3)

Hospital Universitario Araba (HUA)

Vitoria - Gateiz, Araba, Spain

Hospital Universitario Galdakao (HUG)

Galdakao, Bizkaia, Spain

Hospital Universitario Donostia (HUD)

San Sebastián, Guipuzcoa, Spain

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NCT06660446


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