RecruitingNot ApplicableNCT06660446

Exercise During Chemotherapy Treatment As Adjuvant Program in Patients with Lymphoma: EDONOLA Study.

Ejercicio Físico Durante El Tratamiento De Quimioterapia Como Programa Adyuvante En Pacientes Con Linfoma: Estudio EDONOLA

Sponsor

Biogipuzkoa Health Research Institute

Enrollment

180 participants

Start Date

Oct 8, 2024

Study Type

INTERVENTIONAL

Conditions

Lymphoma

Summary

In people diagnosed with lymphoma receiving immunochemotherapy treatment, a combined exercise intervention, as opposed to the general recommendations, will achieve: 1.Improve cardiorespiratory fitness, strength, psychological well-being and quality of life. //2.Reduce fatigue//3.Reduce frailty There is an association between some biological biomarkers with physical capacity and frailty.

Eligibility

Min Age: 18 Years

Inclusion Criteria7

Age: ≥18 years old.
Diagnosis of lymphoma with histological confirmation and requirement of systemic treatment including chemotherapy.
Time available (80 minutes, two days a week for 20 weeks) to carry out physical exercise sessions.
Have a mobile phone to be able to contact the person and download the physical activity level app.
Eastern Cooperative Oncology Group performance status (ECOG) ≤2.
Life expectancy \&gt;12 months.
Availability and desire to participate throughout the study period.

Exclusion Criteria7

Have a contraindication to moderate-high intensity exercise.
Other significant medical disorders: including psychiatric illnesses chronic or recurrent; intellectual disability, musculoskeletal problems, cardiac or pulmonary disorders that interfere with physical exercise; other malignant tumors in the last five years, with the exception of therapeutically controlled skin cancer; any other illness that may be seen affected or aggravated by physical exercise.
Have plans to be outside city more than two weeks.
People who are already physically active (that comply with the recommendations of WHO: \&gt; 150 minutes of exercise moderate/weekly, plus training force two days/week).
Treatment based only with immunotherapy.
Central nervous system involvement due to lymphoma.
Have any important history that limit the capacity of the patient to participate in the study.

Interventions

OTHERExercise

The lymphoma unit of the Donostia University Hospital (HUD) is part of the Onkofrail project that analyzes the impact of a physical activity in older cancer patients. The Onkofrail study has included everything type of solid tumors and very diverse treatments, which is a limitation methodology that could condition the analysis of the results. Therefore, the need of proposing a new PE project in a homogeneous population such as that of people with lymphoma, the most prevalent hemopathy in our environment, which has a great survival, but present important adverse effects secondary to treatment systemic.