Effect of Multimodal Exercise Training in Patients With Multiple Sclerosis
Effect of Multimodal Exercise Training on Disease Activity and Functional Status in Patients With Multiple Sclerosis
Istanbul University - Cerrahpasa
40 participants
Feb 10, 2025
INTERVENTIONAL
Conditions
Summary
The study aims to examine the effects of multimodal exercise training including aerobic, strengthening and balance exercises via face-to-face and asynchronous video-based telerehabilitation on disease activity, disability level, aerobic capacity, physical activity level, balance, fatigue level and quality of life in individuals with multiple sclerosis. Therefore, this study consists of two hypotheses. Hypotheses: H0: Multimodal exercise training has no effect on disease activity and functional status in patients with multiple sclerosis H1: Multimodal exercise training has effects on disease activity and functional status in patients with multiple sclerosis
Eligibility
Inclusion Criteria7
- Being diagnosed with multiple sclerosis by a neurologist
- Volunteering to participate in the study
- Being ambulatory
- EDSS between 3.0-5.5
- Being literate
- Having internet access
- Not having participated in a standardized physiotherapy and rehabilitation program in the last 3 months
Exclusion Criteria6
- Having an orthopedic problem affecting its mobility
- Having psychiatric problems, severe cognitive impairment, or epilepsy in addition to the MS diagnosis
- Blurred vision or visual impairment
- Pregnancy
- Having had an attack or received corticosteroid treatment 3 months before participating in the study
- Having a disease affecting immunological parameters (infection, cancer, etc.)
Interventions
The exercise training consisting of aerobic, strengthening and balance exercises will be applied for 12 weeks/3days for 1hour. One day of the exercise training will be performed in a clinical environment with a physiotherapist, and the other 2 days of the week, participants will be asked to apply asynchronous video-based telerehabilitation over the internet in their own homes. The asynchronous video-based telerehabilitation application will be performed through an account created specifically for the participant on the "www.telenororehab.com" website. The exercise program will be created according to the individual's condition and progression will be provided every 3 weeks. Patients who do not attend 3 consecutive sessions will be excluded from the study.
Participants in the control group will be placed on the waiting list after all evaluation methods have been applied and will be re-evaluated at the end of 12 weeks.
Locations(2)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06676618