RecruitingNot ApplicableNCT06676618

Effect of Multimodal Exercise Training in Patients With Multiple Sclerosis

Effect of Multimodal Exercise Training on Disease Activity and Functional Status in Patients With Multiple Sclerosis

Sponsor

Istanbul University - Cerrahpasa

Enrollment

40 participants

Start Date

Feb 10, 2025

Study Type

INTERVENTIONAL

Conditions

Multiple Sclerosis

Summary

The study aims to examine the effects of multimodal exercise training including aerobic, strengthening and balance exercises via face-to-face and asynchronous video-based telerehabilitation on disease activity, disability level, aerobic capacity, physical activity level, balance, fatigue level and quality of life in individuals with multiple sclerosis. Therefore, this study consists of two hypotheses. Hypotheses: H0: Multimodal exercise training has no effect on disease activity and functional status in patients with multiple sclerosis H1: Multimodal exercise training has effects on disease activity and functional status in patients with multiple sclerosis

Eligibility

Min Age: 20 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This study tests a multimodal exercise training program — combining different types of exercise — in people with multiple sclerosis (MS) to see whether it improves strength, balance, and fatigue. The program is delivered online, making it accessible from home. **You may be eligible if...** - You have been diagnosed with MS by a neurologist - You are able to walk, at least with some support (disability score 3.0–5.5) - You have internet access - You have not taken part in a standardized physical therapy program recently - You are literate (able to read) **You may NOT be eligible if...** - You have a disability score outside the 3.0–5.5 range - You have recently participated in a structured rehab or physiotherapy program - You have other conditions that prevent you from safely exercising - You do not have internet access Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERMultimodal Exercise Training

The exercise training consisting of aerobic, strengthening and balance exercises will be applied for 12 weeks/3days for 1hour. One day of the exercise training will be performed in a clinical environment with a physiotherapist, and the other 2 days of the week, participants will be asked to apply asynchronous video-based telerehabilitation over the internet in their own homes. The asynchronous video-based telerehabilitation application will be performed through an account created specifically for the participant on the "www.telenororehab.com" website. The exercise program will be created according to the individual's condition and progression will be provided every 3 weeks. Patients who do not attend 3 consecutive sessions will be excluded from the study.

OTHERControl Group

Participants in the control group will be placed on the waiting list after all evaluation methods have been applied and will be re-evaluated at the end of 12 weeks.

Locations(2)

Istanbul University-Cerrahpasa

Istanbul, Buyukcekmece, Turkey (Türkiye)

Istanbul University-Cerrahpasa

Istanbul, Istanbul, Turkey (Türkiye)

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NCT06676618

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