RecruitingPhase 2NCT06828796

Early Use of Tacrolimus in HLA-Mismatched Haploidentical Allogeneic Hematopoietic Transplantation With Post-Transplant Cyclophosphamide


Sponsor

Northside Hospital, Inc.

Enrollment

20 participants

Start Date

Jul 3, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

To evalute the safety and efficacy in reducing Cytokine Release Syndrome after hematopoietic stem cell transplantation by introducing immunosuppression earlier in the transplant process


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Cyclophosphamide, a drug called Mycofenolate mofetil, and others for people with hematologic disease and disorders and hematopoietic cell transplant. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 80 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGTacrolimus

Begins Day -1 and continues to Day +90 or Day +180 after transplant

DRUGCyclophosphamide

Given Days +3 and +4 after transplant

DRUGMycofenolate mofetil

Given Day 0 to Day +35 after transplant


Locations(1)

Northside Hospital

Atlanta, Georgia, United States

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NCT06828796


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