RecruitingPhase 3NCT06679270

Open-label Extension Study to Evaluate Metreleptin in Patients With Partial Lipodystrophy

An Open-label Extension of APG-20 Study to Evaluate the Long-term Safety and Efficacy of Daily Subcutaneous Metreleptin Treatment in Subjects With Partial Lipodystrophy


Sponsor

Chiesi Farmaceutici S.p.A.

Enrollment

24 participants

Start Date

Oct 14, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This Phase 3 study is an Open Label Extension of the APG-20 Study To Evaluate the Long-term Safety and Efficacy of Daily Subcutaneous Metreleptin Treatment in Subjects with Partial Lipodystrophy


Eligibility

Min Age: 13 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Metreleptin for people with familial partial lipodystrophy. The study is currently recruiting participants at 7 locations. People eligible for this study include aged 13 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGMetreleptin

Metreleptin is a recombinant human leptin analog that is indicated as an adjunct to diet as replacement therapy to treat the complications of leptin deficiency


Locations(7)

University of Alabama

Birmingham, Alabama, United States

Flourish Research

Boca Raton, Florida, United States

Massachusetts General Hospital

Boston, Massachusetts, United States

University of Michigan

Ann Arbour, Michigan, United States

Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, United States

UT Southwestern Medical Center

Dallas, Texas, United States

The Medical College of Wisconsin

Milwaukee, Wisconsin, United States

View Full Details on ClinicalTrials.gov

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NCT06679270


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