RecruitingNot ApplicableNCT06681818

Novel Method to Assess Hepatic Regeneration and Predict Hepatic Related Morbidity After Partial Hepatectomy

Postoperative Heme Oxygenase Induction and Carbon Monoxide Production as a Novel Method to Assess Hepatic Regeneration and Predict Hepatic Related Morbidity After Partial Hepatectomy

Sponsor

Englewood Hospital and Medical Center

Enrollment

125 participants

Start Date

Nov 21, 2025

Study Type

INTERVENTIONAL

Conditions

Liver Cancer, Adult Liver Regeneration

Summary

the investigators will pursue two specific aims: (1) to monitor the extent of heme oxygenase induction (by measuring endogenous CO production) in relationship to the extent of hepatic resection (2) to assess the production of CO in patients following liver resection and correlate these findings to the rate of liver regeneration and liver function.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study tests a new method of measuring liver regeneration and predicting complications after partial liver removal surgery (hepatectomy), helping surgeons better predict who may have liver-related problems afterward. **You may be eligible if...** - You are 18 or older - You are scheduled to have part of your liver removed for a primary liver condition or for cancer that has spread to the liver - You are able to understand and sign the consent form **You may NOT be eligible if...** - You are under 18 - You are part of a vulnerable population (exceptions made for women of childbearing potential with a negative pregnancy test) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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