RAdiation SEgmentectomy With REsin Microspheres (RASEREM) Study
Ankara University
150 participants
Aug 1, 2025
OBSERVATIONAL
Conditions
Summary
Radiation segmentectomy (RS) refers to selective infusion of Y-90 microspheres to the tumor bearing hepatic segment of hepatic artery. Majority of the data on RS is based on the Glass microspheres experience. Due to different properties of Resin and Glass microspheres description of dose limits to the segment for effectiveness of treatments with Resin microspheres are needed. Based on this background in this study it is aimed to evaluate the safety and efficacy of RS with resin microspheres in HCC patients. Secondly, it is planned to describe the dose limits for complete radiological response.
Eligibility
Inclusion Criteria5
- Patients aged ≥18 years
- Underwent RE as a RS intent (have single or \<3 tumors in same or neighboring 2 segments) for the treatment of HCC or metastatic tumor to liver.
- Presence of extrahepatic disease
- Tumor size less than 8 cm
- Child Pugh Score \<B9
Exclusion Criteria4
- Presence of macrovascular invasion,
- Presence of extrahepatic disease,
- Cholangiocarcinoma or mixed HCC-cholangiocarcinoma
- Not willing to attend follow-up visits.
Locations(20)
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NCT07345247