RecruitingNCT07345247

RAdiation SEgmentectomy With REsin Microspheres (RASEREM) Study

Sponsor

Ankara University

Enrollment

150 participants

Start Date

Aug 1, 2025

Study Type

OBSERVATIONAL

Conditions

Liver Cancer, Adult

Summary

Radiation segmentectomy (RS) refers to selective infusion of Y-90 microspheres to the tumor bearing hepatic segment of hepatic artery. Majority of the data on RS is based on the Glass microspheres experience. Due to different properties of Resin and Glass microspheres description of dose limits to the segment for effectiveness of treatments with Resin microspheres are needed. Based on this background in this study it is aimed to evaluate the safety and efficacy of RS with resin microspheres in HCC patients. Secondly, it is planned to describe the dose limits for complete radiological response.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at outcomes for people with liver cancer (hepatocellular carcinoma, HCC) or liver metastases who were treated with a procedure called radiation segmentectomy using resin microspheres — a targeted internal radiation therapy that delivers radiation beads directly into the liver tumor through the blood vessels. **You may be eligible if...** - You are 18 or older - You had this radiation procedure aimed at curing a single tumor or up to 3 tumors in neighboring sections of the liver - Your tumor is less than 8 cm - Your liver function is relatively preserved (Child Pugh score below B9) **You may NOT be eligible if...** - Cancer has invaded the major blood vessels of the liver - You have cancer outside the liver (extrahepatic disease) - You have a specific type of bile duct cancer (cholangiocarcinoma or mixed tumor) - You are unwilling to come back for follow-up visits Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(20)

Acibadem Adana Hospital

Adana, Turkey (Türkiye)

Adana City Hospital

Adana, Turkey (Türkiye)

Cukurova University

Adana, Turkey (Türkiye)

Bilkent City Hospital

Ankara, Turkey (Türkiye)

Gulhane Education and Research Hospital

Ankara, Turkey (Türkiye)

Hacettepe University

Ankara, Turkey (Türkiye)

Pamukkale University

Denizli, Turkey (Türkiye)

Gazi Yasargil Education and Research Hospital

Diyarbakır, Turkey (Türkiye)

Cam ve Sakura Education and Reseach Hospital

Istanbul, Turkey (Türkiye)

Istanbul Unicersity Cerrahpasa Medical School

Istanbul, Turkey (Türkiye)

Istanbul University Capa Medical School

Istanbul, Turkey (Türkiye)

Marmara University

Istanbul, Turkey (Türkiye)

Acibadem Izmir Hospital

Izmir, Turkey (Türkiye)

Ege University

Izmir, Turkey (Türkiye)

Katip Celebi Education and Research Hospital

Izmir, Turkey (Türkiye)

Erciyes University

Kayseri, Turkey (Türkiye)

Kocaeli University

Kocaeli, Turkey (Türkiye)

Konya Selcuk University

Konya, Turkey (Türkiye)

Inonu University

Malatya, Turkey (Türkiye)

Mersin City Hospital

Mersin, Turkey (Türkiye)

View Full Details on ClinicalTrials.gov

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NCT07345247

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