A Study to Evaluate Effects on Sleep and Safety of RE03 in PTSD Patients With Sleep Disturbances

This study tests an experimental drug called RE03 to see if it helps improve sleep problems in people who have PTSD (post-traumatic stress disorder). **You may be eligible if...** - You are 18–64 years old - You have been diagnosed with PTSD for more than 6 months - You have significant sleep disturbances (difficulty falling or staying asleep, or restless sleep) that have lasted at least a month - You are able to communicate and follow instructions in German **You may NOT be eligible if...** - You work irregular shifts or plan to travel across 2 or more time zones during the study - You have another sleep disorder such as sleep apnea, restless leg syndrome, or narcolepsy - You have bipolar disorder, schizophrenia, obsessive-compulsive disorder, or anorexia - You have a serious heart condition or history of seizures - You are pregnant or breastfeeding - You are currently taking sleep medications, sedatives, or beta-blockers that you cannot stop - You have a recent history of suicidal intent or a suicide attempt in the past year Talk to your doctor to see if this trial is right for you.