RecruitingNot ApplicableNCT06688422

Incentive Spirometry to Improve Outcomes in Lung Cancer Patients Undergoing Concurrent Chemotherapy and Radiation Therapy

Incentive Spirometry for Respiratory Enhancement Pilot Clinical Trial in Lung Cancer Patients Undergoing Concurrent Chemotherapy and Radiation Therapy


Sponsor

The Cooper Health System

Enrollment

100 participants

Start Date

Dec 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to learn if using an incentive spirometer can reduce lung problems in people with advanced lung cancer who are receiving chemotherapy and radiation therapy. The main questions the study aims to answer are: Does using an incentive spirometer lower the chances of developing lung inflammation (pneumonitis)? Does it improve overall survival and quality of life? Participants will: Use an incentive spirometer, a device that helps with deep breathing, 10 times every hour while awake. Continue using the spirometer daily during treatment and for up to three months after treatment. Complete quality of life assessments at the start of the study and at 3, 6, and 12 months. Researchers will compare the results to see if the incentive spirometer helps reduce lung problems and improves participants\' well-being during and after their cancer treatment.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether using an incentive spirometer — a simple breathing device that encourages deep breaths — can help lung cancer patients breathe better and recover more easily during chemotherapy and radiation treatment given at the same time. **You may be eligible if...** - You have been diagnosed with advanced non-small-cell lung cancer - You are scheduled to receive chemotherapy and radiation therapy together - You are 18 or older - You have a good general health status (able to carry out daily activities with minimal difficulty) **You may NOT be eligible if...** - You have had previous lung or chest surgery - You are already enrolled in another breathing-related study - You were using home oxygen before joining the study - You have a pleural effusion (fluid around the lungs), pneumothorax, emphysema, or pneumonitis - You have an active respiratory infection Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEincentive spirometry

The study will have one intervention group of patients using incentive spirometry in addition to standard of care treatment, including chemo/radiation and immunotherapy maintenance. Patients will use the incentive spirometer 10 times (10 breaths) every hour they are awake. Patients will be asked to start using the incentive spirometer as soon as they are enrolled in the study. Patients will be asked to continue to use incentive spirometry daily, including the duration of chemoradiation and up to three months post-treatment.


Locations(1)

MD Anderson Cancer Center at Cooper

Camden, New Jersey, United States

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NCT06688422


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