Pneumonitis Clinical Trials

3 recruitingLast updated: May 5, 2026

There are 22 actively recruiting pneumonitis clinical trials across 19 countries. Studies span Not Applicable, Phase 2, Early Phase 1, Phase 1. Top locations include Cincinnati, Ohio, United States, Houston, Texas, United States, Aurora, Colorado, United States. Updated daily from ClinicalTrials.gov.


Pneumonitis Trials at a Glance

22 actively recruiting trials for pneumonitis are listed on ClinicalTrialsFinder across 6 cities in 19 countries. The largest study group is Not Applicable with 7 trials, with the heaviest enrollment activity in Cincinnati, Houston, and Aurora. Lead sponsors running pneumonitis studies include Amsterdam UMC, location VUmc, Avalyn Pharma Inc., and AHS Cancer Control Alberta.

Browse pneumonitis trials by phase

Treatments under study

About Pneumonitis Clinical Trials

Looking for clinical trials for Pneumonitis? There are currently 3 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Pneumonitis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Pneumonitis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 22 trials

Recruiting
Not Applicable

Incentive Spirometry to Improve Outcomes in Lung Cancer Patients Undergoing Concurrent Chemotherapy and Radiation Therapy

Non-small Cell Lung Cancer (NSCLC)Lung CancerRadiation Induced Lung Injury+2 more
The Cooper Health System100 enrolled1 locationNCT06688422
Recruiting
Phase 2

Prophylactic Inhaled Steroids to Reduce Radiation Pneumonitis Frequency and Severity in Lung Cancer Patients

Radiation Pneumonitis
Instituto Nacional de Cancerologia de Mexico72 enrolled2 locationsNCT03803787
Recruiting
Phase 2

A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis

Progressive Pulmonary FibrosisInterstitial Lung DiseasePulmonary Fibrosis+7 more
Avalyn Pharma Inc.375 enrolled152 locationsNCT06329401
Recruiting
Phase 2

Inhaled Budesonide for REcurrence Prevention and Adjuvant THerapy in Checkpoint Inhibitor Pneumonitis

PneumonitisImmune-related Adverse Event
AHS Cancer Control Alberta94 enrolled1 locationNCT06860542
Recruiting
Not Applicable

Functional Lung Avoidance SPECT-guided Radiation Therapy of Lung Cancer

Lung CancerRadiation PneumonitisPulmonary Disease+2 more
University of Aarhus90 enrolled2 locationsNCT04676828
Recruiting
Not Applicable

Driving Pressure During Surgeries With High Risk for Postoperative Pulmonary Complications

Postoperative Respiratory FailureMechanical PowerPostoperative Pulmonary Atelectasis+7 more
University General Hospital of Patras200 enrolled1 locationNCT07186933
Recruiting
Not Applicable

Functional Lung Avoidance Radiotherapy Guided by 4DCT Pulmonary Ventilation Function Imaging: A Prospective Single-arm Clinical Study

Radiation PneumonitisRadiation Induced Lung InjuryLung Cancer (Including Metastatic Cancer)
The Second Affiliated Hospital of Chongqing Medical University100 enrolled1 locationNCT07339644
Recruiting

Diagnostic Biomarkers for Checkpoint Inhibitor-related Pneumonitis

Checkpoint Inhibitor-related Pneumonitis
Zhou Chengzhi60 enrolled1 locationNCT07340892
Recruiting

Single-Cell Sequencing Analysis of Radiation Pneumonitis Signals In Patients Treated For Cancer With Radiotherapy

Radiation Pneumonitis
NHS Lothian5 enrolled3 locationsNCT06557343
Recruiting

Interstitial Lung Disease Research Unit Biobank

Interstitial Lung DiseaseSarcoidosisPulmonary Fibrosis+2 more
University of Kansas Medical Center1,000 enrolled1 locationNCT05392881
Recruiting

TRANSPIRE: Lung Injury in a Longitudinal Cohort of Pediatric HSCT Patients

Hematopoietic Stem Cell Transplant (HSCT)Thrombotic MicroangiopathiesDiffuse Alveolar Hemorrhage+2 more
Children's Hospital Medical Center, Cincinnati2,000 enrolled9 locationsNCT04098445
Recruiting
Phase 1Phase 2

Single-cell Sequencing of BLF to Guide the Treatment of Radiation Pneumonitis or Immune Checkpoint Inhibitor Pneumonitis

Pneumonitis
Xinqiao Hospital of Chongqing40 enrolled1 locationNCT05455034
Recruiting
Early Phase 1

FAPI PET for Lung Fibrosis

PneumoconiosisRadiation PneumonitisInterstitial Lung Disease+4 more
University of California, Los Angeles30 enrolled1 locationNCT05365802
Recruiting
Not Applicable

Reimagining Interventions for Support and Education in Hypersensitivity Pneumonitis

Hypersensitivity Pneumonitis
Weill Medical College of Cornell University40 enrolled1 locationNCT06811389
Recruiting

P4O2 ILD Extension

Interstitial Lung DiseasePulmonary FibrosisIPF+7 more
Amsterdam UMC, location VUmc450 enrolled1 locationNCT06644144
Recruiting
Not Applicable

Hyperbaric Oxygen in the Prevention of Radiation Pneumonitis

Radiation Pneumonitis
Guangdong Provincial People's Hospital380 enrolled1 locationNCT05189496
Recruiting

Radiotherapy Exposed Lung Injury: Effect on Functioning - Cohort

Breast NeoplasmsRadiation PneumoniaRadiation Pneumonitis+1 more
Meshalkin Research Institute of Pathology of Circulation200 enrolled1 locationNCT06069115
Recruiting
Not Applicable

Skeletal Muscle Function in Interstitial Lung Disease

Interstitial Lung DiseaseIdiopathic Pulmonary FibrosisScleroderma+2 more
University of British Columbia40 enrolled1 locationNCT03800017
Recruiting

Nintedanib for the Prevention of Radiation Pneumonia in Unresectable NSCLC

NSCLCRadiation PneumonitisNintedanib
Second Hospital of Shanxi Medical University40 enrolled7 locationsNCT06570317
Recruiting

A Single-cell Approach to Identify Biomarkers of Pulmonary Toxicity for Immune Checkpoint Blockade

ImmunotherapyImmune-related Adverse EventsPneumonitis, Interstitial
Universitaire Ziekenhuizen KU Leuven60 enrolled1 locationNCT04807127