RecruitingNot ApplicableNCT06688968

Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease

Observational Pilot Study of Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease. What Are the Effects of Mnestic or Hedonic Impairment on Emotion, Reminiscence and Musical Enjoyment

Sponsor

University Hospital, Montpellier

Enrollment

120 participants

Start Date

Feb 4, 2025

Study Type

INTERVENTIONAL

Conditions

Alzheimer Disease, Early Onset Parkinsons Disease with Dementia Non Pharmacological Intervention

Summary

The goal of this Multicenter observational pilot study is to Compare the specifics of musical engagement (behaviors related to music in everyday life) in subjects aged over 60 with Alzheimer s disease, Parkinson s disease and control subjects. The main questions it aims to answer are: 1. The description of different profiles of musical engagement in early-stage AD, in PD and in healthy elderly subjects. 2. The extent of executive, mnestic and hedonic dysfunctions will impact differently on emotional engagement, autobiographical evocation and sensitivity to musical reward, and will therefore enable distinct profiles to be drawn up. Participants will have an intervention consisting of an interview with a neuropsychologist lasting approximately 2 hours, including : * A semi-structured interview to check the participants eligibility and gather demographic data. * Neuropsychological tests and questionnaires will then be administered. * A relative of the study participant will help complete questionnaires.

Eligibility

Min Age: 60 Years

Inclusion Criteria7

years and older
French-speaking and volunteering for the study
Living at home with a relative
Biological diagnosis of probable Alzheimer's disease according to NINCDS-ADRDA criteria (McKhann et al., 1984)
MMSE greater than or equal to 20
Diagnosis of Idiopathic Parkinson's disease
MMSE greater than or equal to 20

Exclusion Criteria12

No known neurological pathologies (epilepsy and other non-degenerative CNS diseases) or psychiatric disorders (chronic psychosis and psychotic episodes)
Autistic disorders
History of stroke or head trauma
Unstable medical condition (cancer)
Subject unable to read and/or write
Hearing impairment without hearing aids
Refusal of consent after information
Persons unable to give consent, research carried out in emergency situations, etc.)
Non-affiliation with a social security scheme
Person deprived of liberty (by judicial or administrative decision, or forced hospitalization)
Person under legal protection (guardianship, curatorship, legal protection)
Person participating in another research project with an exclusion period still in progress

Interventions

BEHAVIORALneuropsychologist interview

It will take place either at the hospital or at the participant's home. This interview will consist of : * socio-demographic data collection * neuropsychological tests: * MMSE test (Mini Mental State Examination) cognitive function * RL-RI-16 test (16-item free recall/indexed recall test) * BECS test (Semantic knowledge assessment battery ) * WCST test (Wisconsin Card Sorting Test ) * Musical Cognition Test * Help from the participant's relative to answer certain questions, in particular the MuseEQ-24 questionnaire

BEHAVIORALquestionnaire

The participant answers questionnaires: * Questionnaire MusEQ-24 self reported (Music Engagement Questionnaire) * Questionnaire BMRQ (Barcelona Reward Music Questionnaire) * Questionnaire SHAPS (Snaith-Hamilton Pleasure Scale) * Questionnaire LARS (Lille's Apathy Rating Scale) * Questionnaire PHQ-9 (Patient Health Questionnaire 9 items)