RecruitingNot ApplicableNCT06688968

Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease

Observational Pilot Study of Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease. What Are the Effects of Mnestic or Hedonic Impairment on Emotion, Reminiscence and Musical Enjoyment


Sponsor

University Hospital, Montpellier

Enrollment

120 participants

Start Date

Feb 4, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this Multicenter observational pilot study is to Compare the specifics of musical engagement (behaviors related to music in everyday life) in subjects aged over 60 with Alzheimer s disease, Parkinson s disease and control subjects. The main questions it aims to answer are: 1. The description of different profiles of musical engagement in early-stage AD, in PD and in healthy elderly subjects. 2. The extent of executive, mnestic and hedonic dysfunctions will impact differently on emotional engagement, autobiographical evocation and sensitivity to musical reward, and will therefore enable distinct profiles to be drawn up. Participants will have an intervention consisting of an interview with a neuropsychologist lasting approximately 2 hours, including : * A semi-structured interview to check the participants eligibility and gather demographic data. * Neuropsychological tests and questionnaires will then be administered. * A relative of the study participant will help complete questionnaires.


Eligibility

Min Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This study is exploring how people with Parkinson's disease or Alzheimer's disease engage with music, and whether musical activities might support their brain health and quality of life. Researchers will examine memory, attention, and emotional responses to music in these groups compared to healthy older adults. **You may be eligible if...** - You are 60 years or older - You speak French and volunteer to participate - You live at home with a relative or caregiver - You have a diagnosis of Parkinson's disease or probable Alzheimer's disease (with a reasonable MMSE cognitive score of 20 or above), OR you are a healthy older adult participating as a comparison group **You may NOT be eligible if...** - You have significant cognitive impairment (MMSE below 20) - You cannot participate due to other health conditions at the investigator's discretion Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALneuropsychologist interview

It will take place either at the hospital or at the participant's home. This interview will consist of : * socio-demographic data collection * neuropsychological tests: * MMSE test (Mini Mental State Examination) cognitive function * RL-RI-16 test (16-item free recall/indexed recall test) * BECS test (Semantic knowledge assessment battery ) * WCST test (Wisconsin Card Sorting Test ) * Musical Cognition Test * Help from the participant's relative to answer certain questions, in particular the MuseEQ-24 questionnaire

BEHAVIORALquestionnaire

The participant answers questionnaires: * Questionnaire MusEQ-24 self reported (Music Engagement Questionnaire) * Questionnaire BMRQ (Barcelona Reward Music Questionnaire) * Questionnaire SHAPS (Snaith-Hamilton Pleasure Scale) * Questionnaire LARS (Lille's Apathy Rating Scale) * Questionnaire PHQ-9 (Patient Health Questionnaire 9 items)


Locations(3)

Montpellier Seniors' Association

Montpellier, Hérault, France

CHU de Montpellier - CEPMo

Montpellier, Hérault, France

CHU de Montpellier - CMRR

Montpellier, Hérault, France

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NCT06688968


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