Alzheimer Disease, Early Onset Clinical Trials

19 recruiting

Frequently Asked Questions

Common questions about Alzheimer Disease, Early Onset clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 119 of 19 trials

Recruiting
Phase 1

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL628 in Participants With Early Alzheimer's Disease

Alzheimer Disease, Early Onset
Denali Therapeutics Inc.68 enrolled1 locationNCT07328451
Recruiting
Phase 3

Donepezil Versus Non-drug Treatment in Alzheimer's Disease.

Alzheimer Disease, Early Onset
Assistance Publique - Hôpitaux de Paris240 enrolled1 locationNCT04661280
Recruiting
Not Applicable

Network-based biOmarker Discovery of Neurodegenerative Diseases Using Multimodal Connectivity

Parkinson DiseaseAlzheimer Disease, Early Onset
Rennes University Hospital120 enrolled1 locationNCT06080659
Recruiting
Phase 1Phase 2

Study of ARO-MAPT-SC in Healthy Subjects and Subjects With Early Alzheimer's Disease

Alzheimer DiseaseAlzheimer Disease, Early Onset
Arrowhead Pharmaceuticals112 enrolled1 locationNCT07221344
Recruiting
Not Applicable

The Ketogenic Diet for Alzheimer's Disease

Alzheimer Disease, Early Onset
Assistance Publique - Hôpitaux de Paris70 enrolled1 locationNCT04701957
Recruiting
Not Applicable

Lifestyle Interventions for the Treatment of Early Onset Alzheimer's Disease Study

Alzheimer Disease, Early Onset
Indiana University60 enrolled1 locationNCT05573490
Recruiting
Not Applicable

Effects of Electrical Stimulation on Verbal Learning in Typical and Atypical Alzheimer's Disease

Alzheimer Disease, Early OnsetAtypical Alzheimer's DiseaseLogopenic Progressive Aphasia
Johns Hopkins University90 enrolled1 locationNCT04122001
Recruiting
Phase 1

A Study to Assess THN391 in Subjects With Alzheimer's Disease

Alzheimer Disease, Early Onset
Therini Bio, Inc.15 enrolled4 locationsNCT06814730
Recruiting
Not Applicable

Transcranial Magnetic Stimulation to Slow Down Cognitive Decline in Alzheimer's Disease

Alzheimer DiseaseAlzheimer Disease, Early Onset
Willem de Haan62 enrolled1 locationNCT07036328
Recruiting
Phase 1

Repurposing Nucleoside Reverse Transcriptase Inhibitors for Treatment of AD

Alzheimer Disease, Early OnsetMild Cognitive ImpairmentModerate Dementia
Butler Hospital35 enrolled2 locationsNCT04500847
Recruiting
Not Applicable

Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease

Alzheimer Disease, Early OnsetParkinsons Disease with DementiaNon Pharmacological Intervention
University Hospital, Montpellier120 enrolled3 locationsNCT06688968
Recruiting

NYSCF Scientific Discovery Biobank

Ovarian CancerCervical CancerDiabetes Mellitus+26 more
New York Stem Cell Foundation Research Institute10,000 enrolled1 locationNCT06203106
Recruiting
Not Applicable

Chronic Treatment of Alzheimer's Disease by Gamma Light and Sound Therapy

Alzheimer DiseaseAlzheimer Disease, Early OnsetAlzheimer Disease, Late Onset+3 more
Massachusetts Institute of Technology50 enrolled1 locationNCT05655195
Recruiting
Not Applicable

A Multifocal TDCS-EEG Protocol for Improving Symptoms of Mild Cognitive Impairment and Early Dementia

DementiaAlzheimer DiseaseAlzheimer Disease, Early Onset+3 more
University of Campania Luigi Vanvitelli50 enrolled1 locationNCT06668610
Recruiting
Not Applicable

MECHANISMS OF NEURONAL RESILIENCE IN ALZHEIMER'S DISEASE AND ITS FOCAL VARIANTS: A PET/MR STUDY

Alzheimer Disease, Early OnsetPosterior Cortical Atrophy
Institut National de la Santé Et de la Recherche Médicale, France45 enrolled2 locationsNCT04150198
Recruiting
Not Applicable

MIMA Pilot Study: MIcrostructure of the Medial Temporal Lobe in Early Alzheimer's Disease

Alzheimer Disease, Early Onset
Rennes University Hospital50 enrolled1 locationNCT06099587
Recruiting
Phase 2Phase 3

GnRH Therapy on Cognition in Down Syndrome

Cognitive DeclineAlzheimer Disease, Early OnsetDown Syndrome+1 more
Nelly Pitteloud56 enrolled1 locationNCT04390646
Recruiting

The Dampness Syndrome of Chinese Medicine Cohort Study

CancerMetabolic DiseaseAging+3 more
Guangzhou University of Traditional Chinese Medicine100,000 enrolled1 locationNCT05315895
Recruiting

Proteomics Study of Mild Cognitive Impairment and Alzheimer's Disease

Alzheimer Disease, Early OnsetProtein; Disease
Guangzhou University of Traditional Chinese Medicine650 enrolled1 locationNCT04804618