WAter Preparation in Crohn's Disease's Imagery
WAter Preparation for Magnetic Resonance Enterography in Crohn's Disease
University Hospital, Toulouse
194 participants
Jan 29, 2025
INTERVENTIONAL
Conditions
Summary
The goal of this clinical trial is to compare distension quality and patient experience of water and polyethylene glycol preparation as oral contrast media in Magnetic Resonance Enterography (MRE) in patients with Crohn's disease. Thus, the main question it aims to answer is: Is water sufficient to interpret MRE from patients with Crohn's disease? Researchers will compare the standard protocol (polyethylene glycol) with water as bowel distension agent to see if it is possible to obtain a satisfying global distension of small bowel. Participants will undergo the same procedures as standard care adding questionnaires and replacing water as the bowel distension agent for the MRE for patient randomized into the experimental group.
Eligibility
Inclusion Criteria2
- Diagnosis of Crohn's Disease,
- need for MRE (determined by patient's gastroenterologist)
Exclusion Criteria5
- < 18 years old,
- inability to obtain an informed consent,
- patient under guardianship or curatorship, allergy to PEG,
- contraindication to MRE (pregnancy, pace maker, claustrophobia in particular), - contraindication to phloroglucinol administration (phenylcetonuria),
- contraindication to gadolinium administration (kidney failure with glomerular filtration rate < 30/mL/1.73m², pregnancy, allergy).
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Interventions
ingestion of 1.5L of water 30min prior MRE acquisition
ingestion of 1.5L of water diluted PEG 45 min prior MRE acquisition (standard protocol)
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06690632