The Association of Psychological Stress with the Efficacy of Neoadjuvant Therapy in Breast Cancer

This study is exploring whether psychological stress levels affect how well neoadjuvant therapy (pre-surgery chemotherapy) works in people with breast cancer. Researchers will measure stress using questionnaires and biological markers to see if stress management could improve treatment outcomes. **You may be eligible if...** - You are 18 or older - You have been newly diagnosed with breast cancer (confirmed by biopsy) - You are about to start neoadjuvant (pre-surgery) chemotherapy or other standard treatment - You have not yet received any cancer treatment - Your general health is good (ECOG 0–1) **You may NOT be eligible if...** - You have already started treatment for breast cancer - Your breast cancer has not been confirmed by pathology - You have significant other health conditions that would interfere with the study Talk to your doctor to see if this trial is right for you.