RecruitingNCT06692049

Gonadal Tissue Cryopreservation for Fertility Preservation in Children with a Disorder of Sex Development

Sponsor

Erin Rowell

Enrollment

250 participants

Start Date

Apr 4, 2018

Study Type

OBSERVATIONAL

Conditions

Disorders of Sex Development DSD, 46,XY DSD, Ovotesticular DSD, Sex Chromosome Disorder of Sex Development, 46,XY Disorder of Sex Development, 46,Xy, Cbx2-Related

Summary

The purpose of this study is to offer gonadal tissue freezing and storage to children who are diagnosed with a disorder of sex development (DSD), who are at increased risk of infertility and certain malignancies (cancer). This study involves the storage of gonadal tissue that is being removed for medical reasons (e.g. prevention of cancer development). It includes the processing and freezing of this gonadal tissue, hopefully for potential future use. The tissue will then be stored long-term until the child wishes to try to use the tissue.

Eligibility

Max Age: 30 Years

Inclusion Criteria2

Individual \< 30 years of age
Children diagnosed with a disorder of sex development who have any risk for malignancy in their gonadal tissue or will have their gonads removed for another clinical indication

Exclusion Criteria5

Pregnant children
Patients likely to retain inherent fertility and reproductive function
Children deemed high risk for perioperative complications
Patients 12-18 unable to provide assent (i.e. significant psychiatric problems/cognitive delay)
Patients 18 and older unable to provide consent (i.e. significant psychiatric problems/cognitive delay)

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