RecruitingNot ApplicableNCT06692114

Efficacy and Influencing Factors of Deep Transcranial Magnetic Stimulation in the Treatment of OCD

A Preliminary Study on the Efficacy and Influencing Factors of Deep Transcranial Magnetic Stimulation in the Treatment of Obsessive-compulsive Disorder


Sponsor

Zhen Wang

Enrollment

70 participants

Start Date

Jul 26, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to explore the efficacy and influencing of accelerated dTMS (deep Transcranial Magnetic Stimulation) treatment in patients with obsessive-compulsive disorder (OCD), and explores the potential neural mechanisms of treatment effect by magnetic resonance imaging (MRI) and electroencephalography (EEG).


Eligibility

Min Age: 18 YearsMax Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at whether deep transcranial magnetic stimulation (dTMS) — a non-invasive procedure that uses magnetic pulses to stimulate specific areas of the brain — can help people with obsessive-compulsive disorder (OCD) that hasn't improved with standard treatments like medication or therapy. **You may be eligible if...** - You are between 18 and 50 years old - You have been diagnosed with OCD based on standard psychiatric criteria - Your OCD symptoms remain severe (high score on the Yale-Brown scale) despite trying medication or cognitive behavioral therapy - Your current treatment plan has been stable for at least 8 weeks - You have at least 9 years of education - You are right-handed **You may NOT be eligible if...** - You have other significant psychiatric conditions besides OCD - You have previously received electroconvulsive therapy (ECT) - You have received brain stimulation therapy (rTMS or tDCS) in the past two months - You have epilepsy, a history of brain injury, or a history of brain surgery - You have implanted devices like a pacemaker, cochlear implant, or intracranial stents - You are pregnant or breastfeeding - You are considered at serious risk of suicide Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DEVICEDeep Transcranial Magnetic Stimulation, DTMS active

The treatment plan is to perform 2 treatments per day for 20 minutes each time, for a total of 28 treatments. Each treatment stimulates at a frequency of 20 Hz for 2 seconds, with a sequence interval of 20 seconds. Each treatment consists of 50 sequences, for a total of 2000 pulses.

DEVICEDeep Transcranial Magnetic Stimulation, DTMS sham

The treatment plan is to perform 2 treatments per day for 20 minutes each time, for a total of 28 treatments. Compared with active treatment, the sham stimulation coil only produced sound and scalp vibration.


Locations(1)

Shanghai Mental Health Center

Shanghai, Shanghai Municipality, China

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06692114


Related Trials