Venetoclax and Decitabine in R/R T-ALL

This study tests a combination of venetoclax (a drug that helps cancer cells die) and decitabine (a low-intensity chemotherapy) in adult patients with T-cell acute lymphoblastic leukemia (T-ALL) that has come back or did not respond to initial treatment. **You may be eligible if...** - You are between 19 and 79 years old - You have T-cell acute lymphoblastic leukemia/lymphoma that relapsed or failed to achieve remission with induction chemotherapy - Your white blood cell count is below 50,000 per microliter at screening (can be reduced with medications beforehand) - Your kidney and liver function meet required thresholds - You are in reasonably good health (ECOG 2 or better) **You may NOT be eligible if...** - You are under 19 or over 79 years old - Your organ function is significantly impaired - Your leukemia is not the T-cell type Talk to your doctor to see if this trial is right for you.